Header logo is


2020


AirCapRL: Autonomous Aerial Human Motion Capture Using Deep Reinforcement Learning
AirCapRL: Autonomous Aerial Human Motion Capture Using Deep Reinforcement Learning

Tallamraju, R., Saini, N., Bonetto, E., Pabst, M., Liu, Y. T., Black, M., Ahmad, A.

IEEE Robotics and Automation Letters, IEEE Robotics and Automation Letters, 5(4):6678 - 6685, IEEE, October 2020, Also accepted and presented in the 2020 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS). (article)

Abstract
In this letter, we introduce a deep reinforcement learning (DRL) based multi-robot formation controller for the task of autonomous aerial human motion capture (MoCap). We focus on vision-based MoCap, where the objective is to estimate the trajectory of body pose, and shape of a single moving person using multiple micro aerial vehicles. State-of-the-art solutions to this problem are based on classical control methods, which depend on hand-crafted system, and observation models. Such models are difficult to derive, and generalize across different systems. Moreover, the non-linearities, and non-convexities of these models lead to sub-optimal controls. In our work, we formulate this problem as a sequential decision making task to achieve the vision-based motion capture objectives, and solve it using a deep neural network-based RL method. We leverage proximal policy optimization (PPO) to train a stochastic decentralized control policy for formation control. The neural network is trained in a parallelized setup in synthetic environments. We performed extensive simulation experiments to validate our approach. Finally, real-robot experiments demonstrate that our policies generalize to real world conditions.

ps

link (url) DOI [BibTex]

2020


link (url) DOI [BibTex]


Biodegradable Untethered Magnetic Hydrogel Milli-Grippers
Biodegradable Untethered Magnetic Hydrogel Milli-Grippers

Goudu, S. R., Yasa, I. C., Hu, X., Ceylan, H., Hu, W., Sitti, M.

Advanced Functional Materials, Wiley Online Library, September 2020 (article)

pi

DOI [BibTex]

DOI [BibTex]


3D Morphable Face Models - Past, Present and Future
3D Morphable Face Models - Past, Present and Future

Egger, B., Smith, W. A. P., Tewari, A., Wuhrer, S., Zollhoefer, M., Beeler, T., Bernard, F., Bolkart, T., Kortylewski, A., Romdhani, S., Theobalt, C., Blanz, V., Vetter, T.

ACM Transactions on Graphics, 39(5), August 2020 (article)

Abstract
In this paper, we provide a detailed survey of 3D Morphable Face Models over the 20 years since they were first proposed. The challenges in building and applying these models, namely capture, modeling, image formation, and image analysis, are still active research topics, and we review the state-of-the-art in each of these areas. We also look ahead, identifying unsolved challenges, proposing directions for future research and highlighting the broad range of current and future applications.

ps

project page pdf preprint DOI [BibTex]

project page pdf preprint DOI [BibTex]


Analysis of motor development within the first year of life: 3-{D} motion tracking without markers for early detection of developmental disorders
Analysis of motor development within the first year of life: 3-D motion tracking without markers for early detection of developmental disorders

Parisi, C., Hesse, N., Tacke, U., Rocamora, S. P., Blaschek, A., Hadders-Algra, M., Black, M. J., Heinen, F., Müller-Felber, W., Schroeder, A. S.

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 63, pages: 881–890, July 2020 (article)

Abstract
Children with motor development disorders benefit greatly from early interventions. An early diagnosis in pediatric preventive care (U2–U5) can be improved by automated screening. Current approaches to automated motion analysis, however, are expensive, require lots of technical support, and cannot be used in broad clinical application. Here we present an inexpensive, marker-free video analysis tool (KineMAT) for infants, which digitizes 3‑D movements of the entire body over time allowing automated analysis in the future. Three-minute video sequences of spontaneously moving infants were recorded with a commercially available depth-imaging camera and aligned with a virtual infant body model (SMIL model). The virtual image generated allows any measurements to be carried out in 3‑D with high precision. We demonstrate seven infants with different diagnoses. A selection of possible movement parameters was quantified and aligned with diagnosis-specific movement characteristics. KineMAT and the SMIL model allow reliable, three-dimensional measurements of spontaneous activity in infants with a very low error rate. Based on machine-learning algorithms, KineMAT can be trained to automatically recognize pathological spontaneous motor skills. It is inexpensive and easy to use and can be developed into a screening tool for preventive care for children.

ps

pdf on-line w/ sup mat DOI [BibTex]

pdf on-line w/ sup mat DOI [BibTex]


Learning and Tracking the {3D} Body Shape of Freely Moving Infants from {RGB-D} sequences
Learning and Tracking the 3D Body Shape of Freely Moving Infants from RGB-D sequences

Hesse, N., Pujades, S., Black, M., Arens, M., Hofmann, U., Schroeder, S.

IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI), 42(10):2540-2551, 2020 (article)

Abstract
Statistical models of the human body surface are generally learned from thousands of high-quality 3D scans in predefined poses to cover the wide variety of human body shapes and articulations. Acquisition of such data requires expensive equipment, calibration procedures, and is limited to cooperative subjects who can understand and follow instructions, such as adults. We present a method for learning a statistical 3D Skinned Multi-Infant Linear body model (SMIL) from incomplete, low-quality RGB-D sequences of freely moving infants. Quantitative experiments show that SMIL faithfully represents the RGB-D data and properly factorizes the shape and pose of the infants. To demonstrate the applicability of SMIL, we fit the model to RGB-D sequences of freely moving infants and show, with a case study, that our method captures enough motion detail for General Movements Assessment (GMA), a method used in clinical practice for early detection of neurodevelopmental disorders in infants. SMIL provides a new tool for analyzing infant shape and movement and is a step towards an automated system for GMA.

ps

pdf Journal DOI [BibTex]

pdf Journal DOI [BibTex]


Statistical reprogramming of macroscopic self-assembly with dynamic boundaries
Statistical reprogramming of macroscopic self-assembly with dynamic boundaries

Culha, U., Davidson, Z. S., Mastrangeli, M., Sitti, M.

Proceedings of the National Academy of Sciences, 117(21):11306-11313, May 2020 (article)

Abstract
Self-assembly is a ubiquitous process that can generate complex and functional structures via local interactions among a large set of simpler components. The ability to program the self-assembly pathway of component sets elucidates fundamental physics and enables alternative competitive fabrication technologies. Reprogrammability offers further opportunities for tuning structural and material properties but requires reversible selection from multistable self-assembling patterns, which remains a challenge. Here, we show statistical reprogramming of two-dimensional (2D), noncompact self-assembled structures by the dynamic confinement of orbitally shaken and magnetically repulsive millimeter-scale particles. Under a constant shaking regime, we control the rate of radius change of an assembly arena via moving hard boundaries and select among a finite set of self-assembled patterns repeatably and reversibly. By temporarily trapping particles in topologically identified stable states, we also demonstrate 2D reprogrammable stiffness and three-dimensional (3D) magnetic clutching of the self-assembled structures. Our reprogrammable system has prospective implications for the design of granular materials in a multitude of physical scales where out-of-equilibrium self-assembly can be realized with different numbers or types of particles. Our dynamic boundary regulation may also enable robust bottom-up control strategies for novel robotic assembly applications by designing more complex spatiotemporal interactions using mobile robots.

pi

DOI [BibTex]

DOI [BibTex]


General Movement Assessment from videos of computed {3D} infant body models is equally effective compared to conventional {RGB} Video rating
General Movement Assessment from videos of computed 3D infant body models is equally effective compared to conventional RGB Video rating

Schroeder, S., Hesse, N., Weinberger, R., Tacke, U., Gerstl, L., Hilgendorff, A., Heinen, F., Arens, M., Bodensteiner, C., Dijkstra, L. J., Pujades, S., Black, M., Hadders-Algra, M.

Early Human Development, 144, May 2020 (article)

Abstract
Background: General Movement Assessment (GMA) is a powerful tool to predict Cerebral Palsy (CP). Yet, GMA requires substantial training hampering its implementation in clinical routine. This inspired a world-wide quest for automated GMA. Aim: To test whether a low-cost, marker-less system for three-dimensional motion capture from RGB depth sequences using a whole body infant model may serve as the basis for automated GMA. Study design: Clinical case study at an academic neurodevelopmental outpatient clinic. Subjects: Twenty-nine high-risk infants were recruited and assessed at their clinical follow-up at 2-4 month corrected age (CA). Their neurodevelopmental outcome was assessed regularly up to 12-31 months CA. Outcome measures: GMA according to Hadders-Algra by a masked GMA-expert of conventional and computed 3D body model (“SMIL motion”) videos of the same GMs. Agreement between both GMAs was assessed, and sensitivity and specificity of both methods to predict CP at ≥12 months CA. Results: The agreement of the two GMA ratings was substantial, with κ=0.66 for the classification of definitely abnormal (DA) GMs and an ICC of 0.887 (95% CI 0.762;0.947) for a more detailed GM-scoring. Five children were diagnosed with CP (four bilateral, one unilateral CP). The GMs of the child with unilateral CP were twice rated as mildly abnormal. DA-ratings of both videos predicted bilateral CP well: sensitivity 75% and 100%, specificity 88% and 92% for conventional and SMIL motion videos, respectively. Conclusions: Our computed infant 3D full body model is an attractive starting point for automated GMA in infants at risk of CP.

ps

DOI [BibTex]

DOI [BibTex]


Learning Multi-Human Optical Flow
Learning Multi-Human Optical Flow

Ranjan, A., Hoffmann, D. T., Tzionas, D., Tang, S., Romero, J., Black, M. J.

International Journal of Computer Vision (IJCV), (128):873-890, April 2020 (article)

Abstract
The optical flow of humans is well known to be useful for the analysis of human action. Recent optical flow methods focus on training deep networks to approach the problem. However, the training data used by them does not cover the domain of human motion. Therefore, we develop a dataset of multi-human optical flow and train optical flow networks on this dataset. We use a 3D model of the human body and motion capture data to synthesize realistic flow fields in both single-and multi-person images. We then train optical flow networks to estimate human flow fields from pairs of images. We demonstrate that our trained networks are more accurate than a wide range of top methods on held-out test data and that they can generalize well to real image sequences. The code, trained models and the dataset are available for research.

ps

pdf DOI poster link (url) DOI [BibTex]

pdf DOI poster link (url) DOI [BibTex]


Real Time Trajectory Prediction Using Deep Conditional Generative Models
Real Time Trajectory Prediction Using Deep Conditional Generative Models

Gomez-Gonzalez, S., Prokudin, S., Schölkopf, B., Peters, J.

IEEE Robotics and Automation Letters, 5(2):970-976, IEEE, January 2020 (article)

ei ps

arXiv DOI [BibTex]

arXiv DOI [BibTex]


Thermal Effects on the Crystallization Kinetics, and Interfacial Adhesion of Single-Crystal Phase-Change Gallium
Thermal Effects on the Crystallization Kinetics, and Interfacial Adhesion of Single-Crystal Phase-Change Gallium

Yunusa, M., Lahlou, A., Sitti, M.

Advanced Materials, Wiley Online Library, 2020 (article)

Abstract
Although substrates play an important role upon crystallization of supercooled liquids, the influences of surface temperature and thermal property have remained elusive. Here, the crystallization of supercooled phase‐change gallium (Ga) on substrates with different thermal conductivity is studied. The effect of interfacial temperature on the crystallization kinetics, which dictates thermo‐mechanical stresses between the substrate and the crystallized Ga, is investigated. At an elevated surface temperature, close to the melting point of Ga, an extended single‐crystal growth of Ga on dielectric substrates due to layering effect and annealing is realized without the application of external fields. Adhesive strength at the interfaces depends on the thermal conductivity and initial surface temperature of the substrates. This insight can be applicable to other liquid metals for industrial applications, and sheds more light on phase‐change memory crystallization.

pi

[BibTex]


Nanoerythrosome-functionalized biohybrid microswimmers
Nanoerythrosome-functionalized biohybrid microswimmers

Buss, N., Yasa, O., Alapan, Y., Akolpoglu, M. B., Sitti, M.

APL Bioengineering, 4, AIP Publishing LLC, 2020 (article)

pi

[BibTex]

[BibTex]


Injectable Nanoelectrodes Enable Wireless Deep Brain Stimulation of Native Tissue in Freely Moving Mice
Injectable Nanoelectrodes Enable Wireless Deep Brain Stimulation of Native Tissue in Freely Moving Mice

Kozielski, K. L., Jahanshahi, A., Gilbert, H. B., Yu, Y., Erin, O., Francisco, D., Alosaimi, F., Temel, Y., Sitti, M.

bioRxiv, Cold Spring Harbor Laboratory, 2020 (article)

pi

[BibTex]

[BibTex]


Magnetically Actuated Soft Capsule Endoscope for Fine-Needle Biopsy
Magnetically Actuated Soft Capsule Endoscope for Fine-Needle Biopsy

Son, D., Gilbert, H., Sitti, M.

Soft robotics, Mary Ann Liebert, Inc., publishers 140 Huguenot Street, 3rd Floor New …, 2020 (article)

pi

[BibTex]

[BibTex]


Mechanical coupling of puller and pusher active microswimmers influences motility
Mechanical coupling of puller and pusher active microswimmers influences motility

Singh, A. V., Kishore, V., Santamauro, G., Yasa, O., Bill, J., Sitti, M.

Langmuir, ACS Publications, 2020 (article)

pi

[BibTex]


Microribbons composed of directionally self-assembled nanoflakes as highly stretchable ionic neural electrodes
Microribbons composed of directionally self-assembled nanoflakes as highly stretchable ionic neural electrodes

Zhang, M., Guo, R., Chen, K., Wang, Y., Niu, J., Guo, Y., Zhang, Y., Yin, Z., Xia, K., Zhou, B., Wang, H., He, W., Liu, J., Sitti, M., Zhang, Y.

Proceedings of the National Academy of Sciences, National Academy of Sciences, 2020 (article)

pi

link (url) DOI [BibTex]

link (url) DOI [BibTex]


Reprogrammable shape morphing of magnetic soft machines
Reprogrammable shape morphing of magnetic soft machines

Alapan, Y., Karacakol, A. C., Guzelhan, S. N., Isik, I., Sitti, M.

Science Advances, 6, American Association for the Advancement of Science, 2020 (article)

pi

[BibTex]

[BibTex]


no image
Analytical classical density functionals from an equation learning network

Lin, S., Martius, G., Oettel, M.

The Journal of Chemical Physics, 152(2):021102, 2020, arXiv preprint \url{https://arxiv.org/abs/1910.12752} (article)

al

Preprint_PDF DOI [BibTex]

Preprint_PDF DOI [BibTex]


Controlling two-dimensional collective formation and cooperative behavior of magnetic microrobot swarms
Controlling two-dimensional collective formation and cooperative behavior of magnetic microrobot swarms

Dong, X., Sitti, M.

The International Journal of Robotics Research, 2020 (article)

Abstract
Magnetically actuated mobile microrobots can access distant, enclosed, and small spaces, such as inside microfluidic channels and the human body, making them appealing for minimally invasive tasks. Despite their simplicity when scaling down, creating collective microrobots that can work closely and cooperatively, as well as reconfigure their formations for different tasks, would significantly enhance their capabilities such as manipulation of objects. However, a challenge of realizing such cooperative magnetic microrobots is to program and reconfigure their formations and collective motions with under-actuated control signals. This article presents a method of controlling 2D static and time-varying formations among collective self-repelling ferromagnetic microrobots (100 μm to 350 μm in diameter, up to 260 in number) by spatially and temporally programming an external magnetic potential energy distribution at the air–water interface or on solid surfaces. A general design method is introduced to program external magnetic potential energy using ferromagnets. A predictive model of the collective system is also presented to predict the formation and guide the design procedure. With the proposed method, versatile complex static formations are experimentally demonstrated and the programmability and scaling effects of formations are analyzed. We also demonstrate the collective mobility of these magnetic microrobots by controlling them to exhibit bio-inspired collective behaviors such as aggregation, directional motion with arbitrary swarm headings, and rotational swarming motion. Finally, the functions of the produced microrobotic swarm are demonstrated by controlling them to navigate through cluttered environments and complete reconfigurable cooperative manipulation tasks.

pi

DOI [BibTex]


Magnetic Resonance Imaging System--Driven Medical Robotics
Magnetic Resonance Imaging System–Driven Medical Robotics

Erin, O., Boyvat, M., Tiryaki, M. E., Phelan, M., Sitti, M.

Advanced Intelligent Systems, 2, Wiley Online Library, 2020 (article)

Abstract
Magnetic resonance imaging (MRI) system–driven medical robotics is an emerging field that aims to use clinical MRI systems not only for medical imaging but also for actuation, localization, and control of medical robots. Submillimeter scale resolution of MR images for soft tissues combined with the electromagnetic gradient coil–based magnetic actuation available inside MR scanners can enable theranostic applications of medical robots for precise image‐guided minimally invasive interventions. MRI‐driven robotics typically does not introduce new MRI instrumentation for actuation but instead focuses on converting already available instrumentation for robotic purposes. To use the advantages of this technology, various medical devices such as untethered mobile magnetic robots and tethered active catheters have been designed to be powered magnetically inside MRI systems. Herein, the state‐of‐the‐art progress, challenges, and future directions of MRI‐driven medical robotic systems are reviewed.

pi

[BibTex]

[BibTex]


Characterization and Thermal Management of a DC Motor-Driven Resonant Actuator for Miniature Mobile Robots with Oscillating Limbs
Characterization and Thermal Management of a DC Motor-Driven Resonant Actuator for Miniature Mobile Robots with Oscillating Limbs

Colmenares, D., Kania, R., Liu, M., Sitti, M.

arXiv preprint arXiv:2002.00798, 2020 (article)

Abstract
In this paper, we characterize the performance of and develop thermal management solutions for a DC motor-driven resonant actuator developed for flapping wing micro air vehicles. The actuator, a DC micro-gearmotor connected in parallel with a torsional spring, drives reciprocal wing motion. Compared to the gearmotor alone, this design increased torque and power density by 161.1% and 666.8%, respectively, while decreasing the drawn current by 25.8%. Characterization of the actuator, isolated from nonlinear aerodynamic loading, results in standard metrics directly comparable to other actuators. The micro-motor, selected for low weight considerations, operates at high power for limited duration due to thermal effects. To predict system performance, a lumped parameter thermal circuit model was developed. Critical model parameters for this micro-motor, two orders of magnitude smaller than those previously characterized, were identified experimentally. This included the effects of variable winding resistance, bushing friction, speed-dependent forced convection, and the addition of a heatsink. The model was then used to determine a safe operation envelope for the vehicle and to design a weight-optimal heatsink. This actuator design and thermal modeling approach could be applied more generally to improve the performance of any miniature mobile robot or device with motor-driven oscillating limbs or loads.

pi

[BibTex]


Pros and Cons: Magnetic versus Optical Microrobots
Pros and Cons: Magnetic versus Optical Microrobots

Sitti, M., Wiersma, D. S.

Advanced Materials, Wiley Online Library, 2020 (article)

Abstract
Mobile microrobotics has emerged as a new robotics field within the last decade to create untethered tiny robots that can access and operate in unprecedented, dangerous, or hard‐to‐reach small spaces noninvasively toward disruptive medical, biotechnology, desktop manufacturing, environmental remediation, and other potential applications. Magnetic and optical actuation methods are the most widely used actuation methods in mobile microrobotics currently, in addition to acoustic and biological (cell‐driven) actuation approaches. The pros and cons of these actuation methods are reported here, depending on the given context. They can both enable long‐range, fast, and precise actuation of single or a large number of microrobots in diverse environments. Magnetic actuation has unique potential for medical applications of microrobots inside nontransparent tissues at high penetration depths, while optical actuation is suitable for more biotechnology, lab‐/organ‐on‐a‐chip, and desktop manufacturing types of applications with much less surface penetration depth requirements or with transparent environments. Combining both methods in new robot designs can have a strong potential of combining the pros of both methods. There is still much progress needed in both actuation methods to realize the potential disruptive applications of mobile microrobots in real‐world conditions.

pi

[BibTex]

[BibTex]


Selectively Controlled Magnetic Microrobots with Opposing Helices
Selectively Controlled Magnetic Microrobots with Opposing Helices

Giltinan, J., Katsamba, P., Wang, W., Lauga, E., Sitti, M.

Applied Physics Letters, 116, AIP Publishing LLC, 2020 (article)

pi

[BibTex]

[BibTex]


Microscale Polarization Color Pixels from Liquid Crystal Elastomers
Microscale Polarization Color Pixels from Liquid Crystal Elastomers

Guo, Y., Shahsavan, H., Sitti, M.

Advanced Optical Materials, Wiley Online Library, 2020 (article)

pi

[BibTex]

[BibTex]


Wearable and Stretchable Strain Sensors: Materials, Sensing Mechanisms, and Applications
Wearable and Stretchable Strain Sensors: Materials, Sensing Mechanisms, and Applications

Souri, H., Banerjee, H., Jusufi, A., Radacsi, N., Stokes, A. A., Park, I., Sitti, M., Amjadi, M.

Advanced Intelligent Systems, 2020 (article)

bio pi

link (url) DOI [BibTex]

link (url) DOI [BibTex]


Ultrasound-guided Wireless Tubular Robotic Anchoring System
Ultrasound-guided Wireless Tubular Robotic Anchoring System

Wang, T., Hu, W., Ren, Z., Sitti, M.

IEEE Robotics and Automation Letters, 5, pages: 4859 - 4866, IEEE, 2020 (article)

pi

link (url) DOI [BibTex]

link (url) DOI [BibTex]


In-air fast response and high speed jumping and rolling of a light-driven hydrogel actuator
In-air fast response and high speed jumping and rolling of a light-driven hydrogel actuator

Li, M., Wang, X., Dong, B., Sitti, M.

Nature Communications, 11, Nature Publishing Group, 2020 (article)

pi

[BibTex]

[BibTex]


Cohesive self-organization of mobile microrobotic swarms
Cohesive self-organization of mobile microrobotic swarms

Yigit, B., Alapan, Y., Sitti, M.

arXiv preprint arXiv:1907.05856, 2020 (article)

pi

[BibTex]

[BibTex]


Bio-inspired Flexible Twisting Wings Increase Lift and Efficiency of a Flapping Wing Micro Air Vehicle
Bio-inspired Flexible Twisting Wings Increase Lift and Efficiency of a Flapping Wing Micro Air Vehicle

Colmenares, D., Kania, R., Zhang, W., Sitti, M.

arXiv preprint arXiv:2001.11586, 2020 (article)

Abstract
We investigate the effect of wing twist flexibility on lift and efficiency of a flapping-wing micro air vehicle capable of liftoff. Wings used previously were chosen to be fully rigid due to modeling and fabrication constraints. However, biological wings are highly flexible and other micro air vehicles have successfully utilized flexible wing structures for specialized tasks. The goal of our study is to determine if dynamic twisting of flexible wings can increase overall aerodynamic lift and efficiency. A flexible twisting wing design was found to increase aerodynamic efficiency by 41.3%, translational lift production by 35.3%, and the effective lift coefficient by 63.7% compared to the rigid-wing design. These results exceed the predictions of quasi-steady blade element models, indicating the need for unsteady computational fluid dynamics simulations of twisted flapping wings.

pi

[BibTex]

[BibTex]


Acoustically powered surface-slipping mobile microrobots
Acoustically powered surface-slipping mobile microrobots

Aghakhani, A., Yasa, O., Wrede, P., Sitti, M.

Proceedings of the National Academy of Sciences, 117, National Acad Sciences, 2020 (article)

Abstract
Untethered synthetic microrobots have significant potential to revolutionize minimally invasive medical interventions in the future. However, their relatively slow speed and low controllability near surfaces typically are some of the barriers standing in the way of their medical applications. Here, we introduce acoustically powered microrobots with a fast, unidirectional surface-slipping locomotion on both flat and curved surfaces. The proposed three-dimensionally printed, bullet-shaped microrobot contains a spherical air bubble trapped inside its internal body cavity, where the bubble is resonated using acoustic waves. The net fluidic flow due to the bubble oscillation orients the microrobot's axisymmetric axis perpendicular to the wall and then propels it laterally at very high speeds (up to 90 body lengths per second with a body length of 25 µm) while inducing an attractive force toward the wall. To achieve unidirectional locomotion, a small fin is added to the microrobot’s cylindrical body surface, which biases the propulsion direction. For motion direction control, the microrobots are coated anisotropically with a soft magnetic nanofilm layer, allowing steering under a uniform magnetic field. Finally, surface locomotion capability of the microrobots is demonstrated inside a three-dimensional circular cross-sectional microchannel under acoustic actuation. Overall, the combination of acoustic powering and magnetic steering can be effectively utilized to actuate and navigate these microrobots in confined and hard-to-reach body location areas in a minimally invasive fashion.

pi

[BibTex]

[BibTex]


no image
Morphology-Dependent Immunogenicity Obliges a Compromise on the Locomotion-Focused Design of Medical Microrobots

Ceren, , Hakan, , Ugur, , Anna-Maria, , Metin,

Science Robotics, 2020 (article) Accepted

pi

[BibTex]

[BibTex]


Selection for Function: From Chemically Synthesized Prototypes to 3D-Printed Microdevices
Selection for Function: From Chemically Synthesized Prototypes to 3D-Printed Microdevices

Bachmann, F., Giltinan, J., Codutti, A., Klumpp, S., Sitti, M., Faivre, D.

Advanced Intelligent Systems, 2020 (article)

pi

[BibTex]

[BibTex]


Biosynthetic self-healing materials for soft machines
Biosynthetic self-healing materials for soft machines

Pena-Francesch, A., Jung, H., Demirel, M. C., Sitti, M.

Nature Materials , 2020 (article)

pi

DOI [BibTex]

DOI [BibTex]


Carbon nitride-based light-driven microswimmers with intrinsic photocharging ability
Carbon nitride-based light-driven microswimmers with intrinsic photocharging ability

Sridhar, V., Podjaski, F., Kröger, J., Jiménez-Solano, A., Park, B., Lotsch, B. V., Sitti, M.

Proceedings of the National Academy of Sciences, National Acad Sciences, 2020 (article)

pi

[BibTex]

[BibTex]


Bioinspired underwater locomotion of light-driven liquid crystal gels
Bioinspired underwater locomotion of light-driven liquid crystal gels

Shahsavan, H., Aghakhani, A., Zeng, H., Guo, Y., Davidson, Z. S., Priimagi, A., Sitti, M.

Proceedings of the National Academy of Sciences, National Acad Sciences, 2020 (article)

Abstract
Untethered dynamic shape programming and control of soft materials have significant applications in technologies such as soft robots, medical devices, organ-on-a-chip, and optical devices. Here, we present a solution to remotely actuate and move soft materials underwater in a fast, efficient, and controlled manner using photoresponsive liquid crystal gels (LCGs). LCG constructs with engineered molecular alignment show a low and sharp phase-transition temperature and experience considerable density reduction by light exposure, thereby allowing rapid and reversible shape changes. We demonstrate different modes of underwater locomotion, such as crawling, walking, jumping, and swimming, by localized and time-varying illumination of LCGs. The diverse locomotion modes of smart LCGs can provide a new toolbox for designing efficient light-fueled soft robots in fluid-immersed media.

pi

[BibTex]

[BibTex]


Additive manufacturing of cellulose-based materials with continuous, multidirectional stiffness gradients
Additive manufacturing of cellulose-based materials with continuous, multidirectional stiffness gradients

Giachini, P., Gupta, S., Wang, W., Wood, D., Yunusa, M., Baharlou, E., Sitti, M., Menges, A.

Science Advances, 6, American Association for the Advancement of Science, 2020 (article)

Abstract
Functionally graded materials (FGMs) enable applications in fields such as biomedicine and architecture, but their fabrication suffers from shortcomings in gradient continuity, interfacial bonding, and directional freedom. In addition, most commercial design software fail to incorporate property gradient data, hindering explorations of the design space of FGMs. Here, we leveraged a combined approach of materials engineering and digital processing to enable extrusion-based multimaterial additive manufacturing of cellulose-based tunable viscoelastic materials with continuous, high-contrast, and multidirectional stiffness gradients. A method to engineer sets of cellulose-based materials with similar compositions, yet distinct mechanical and rheological properties, was established. In parallel, a digital workflow was developed to embed gradient information into design models with integrated fabrication path planning. The payoff of integrating these physical and digital tools is the ability to achieve the same stiffness gradient in multiple ways, opening design possibilities previously limited by the rigid coupling of material and geometry.

pi

[BibTex]

[BibTex]


no image
Introducing Progress in Biomedical Engineering; Issue 2 Vol 2

Sitti, M.

Progress in Biomedical Engineering, IOP Publishing, 2020 (article)

pi

[BibTex]

[BibTex]


Multi-wavelength steerable visible light-driven magnetic CoO-TiO2 microswimmers
Multi-wavelength steerable visible light-driven magnetic CoO-TiO2 microswimmers

Sridhar, V., Park, B., Guo, S., van Aken, P. A., Sitti, M.

ACS Applied Materials \& Interfaces, ACS Publications, 2020 (article)

pi

[BibTex]

[BibTex]

2016


Bioengineered and biohybrid bacteria-based systems for drug delivery
Bioengineered and biohybrid bacteria-based systems for drug delivery

Hosseinidoust, Z., Mostaghaci, B., Yasa, O., Park, B., Singh, A. V., Sitti, M.

Advanced Drug Delivery Reviews, 106, pages: 27-44, Elsevier, November 2016 (article)

Abstract
The use of bacterial cells as agents of medical therapy has a long history. Research that was ignited over a century ago with the accidental infection of cancer patients has matured into a platform technology that offers the promise of opening up new potential frontiers in medical treatment. Bacterial cells exhibit unique characteristics that make them well-suited as smart drug delivery agents. Our ability to genetically manipulate the molecular machinery of these cells enables the customization of their therapeutic action as well as its precise tuning and spatio-temporal control, allowing for the design of unique, complex therapeutic functions, unmatched by current drug delivery systems. Early results have been promising, but there are still many important challenges that must be addressed. We present a review of promises and challenges of employing bioengineered bacteria in drug delivery systems and introduce the biohybrid design concept as a new additional paradigm in bacteria-based drug delivery.

pi

DOI Project Page [BibTex]

2016


DOI Project Page [BibTex]


Creating body shapes from verbal descriptions by linking similarity spaces
Creating body shapes from verbal descriptions by linking similarity spaces

Hill, M. Q., Streuber, S., Hahn, C. A., Black, M. J., O’Toole, A. J.

Psychological Science, 27(11):1486-1497, November 2016, (article)

Abstract
Brief verbal descriptions of bodies (e.g. curvy, long-legged) can elicit vivid mental images. The ease with which we create these mental images belies the complexity of three-dimensional body shapes. We explored the relationship between body shapes and body descriptions and show that a small number of words can be used to generate categorically accurate representations of three-dimensional bodies. The dimensions of body shape variation that emerged in a language-based similarity space were related to major dimensions of variation computed directly from three-dimensional laser scans of 2094 bodies. This allowed us to generate three-dimensional models of people in the shape space using only their coordinates on analogous dimensions in the language-based description space. Human descriptions of photographed bodies and their corresponding models matched closely. The natural mapping between the spaces illustrates the role of language as a concise code for body shape, capturing perceptually salient global and local body features.

ps

pdf [BibTex]

pdf [BibTex]


A 5-D localization method for a magnetically manipulated untethered robot using a 2-D array of Hall-effect sensors
A 5-D localization method for a magnetically manipulated untethered robot using a 2-D array of Hall-effect sensors

Son, D., Yim, S., Sitti, M.

IEEE/ASME Transactions on Mechatronics, 21(2):708-716, IEEE, October 2016 (article)

Abstract
This paper introduces a new five-dimensional localization method for an untethered meso-scale magnetic robot, which is manipulated by a computer-controlled electromagnetic system. The developed magnetic localization setup is a two-dimensional array of mono-axial Hall-effect sensors, which measure the perpendicular magnetic fields at their given positions. We introduce two steps for localizing a magnetic robot more accurately. First, the dipole modeled magnetic field of the electromagnet is subtracted from the measured data in order to determine the robot's magnetic field. Secondly, the subtracted magnetic field is twice differentiated in the perpendicular direction of the array, so that the effect of the electromagnetic field in the localization process is minimized. Five variables regarding the position and orientation of the robot are determined by minimizing the error between the measured magnetic field and the modeled magnetic field in an optimization method. The resulting position error is 2.1±0.8 mm and angular error is 6.7±4.3° within the applicable range (5 cm) of magnetic field sensors at 200 Hz. The proposed localization method would be used for the position feedback control of untethered magnetic devices or robots for medical applications in the future.

pi

DOI Project Page [BibTex]

DOI Project Page [BibTex]


High-Performance Multiresponsive Paper Actuators
High-Performance Multiresponsive Paper Actuators

Amjadi, M., Sitti, M.

ACS Nano, 10(11):10202-10210, American Chemical Society, October 2016 (article)

Abstract
There is an increasing demand for soft actuators because of their importance in soft robotics, artificial muscles, biomimetic devices, and beyond. However, the development of soft actuators capable of low-voltage operation, powerful actuation, and programmable shape-changing is still challenging. In this work, we propose programmable bilayer actuators that operate based on the large hygroscopic contraction of the copy paper and simultaneously large thermal expansion of the polypropylene film upon increasing the temperature. The electrothermally activated bending actuators can function with low voltages (≤ 8 V), low input electric power per area (P ≤ 0.14 W cm–2), and low temperature changes (≤ 35 °C). They exhibit reversible shape-changing behavior with curvature radii up to 1.07 cm–1 and bending angle of 360°, accompanied by powerful actuation. Besides the electrical activation, they can be powered by humidity or light irradiation. We finally demonstrate the use of our paper actuators as a soft gripper robot and a lightweight paper wing for aerial robotics.

pi

DOI Project Page Project Page [BibTex]

DOI Project Page Project Page [BibTex]