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62 results (View BibTeX file of all listed publications)

2018

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Role of symmetry in driven propulsion at low Reynolds number

Sachs, J., Morozov, K. I., Kenneth, O., Qiu, T., Segreto, N., Fischer, P., Leshansky, A. M.

Phys. Rev. E, 98(6):063105, American Physical Society, December 2018 (article)

Abstract
We theoretically and experimentally investigate low-Reynolds-number propulsion of geometrically achiral planar objects that possess a dipole moment and that are driven by a rotating magnetic field. Symmetry considerations (involving parity, $\widehat{P}$, and charge conjugation, $\widehat{C}$) establish correspondence between propulsive states depending on orientation of the dipolar moment. Although basic symmetry arguments do not forbid individual symmetric objects to efficiently propel due to spontaneous symmetry breaking, they suggest that the average ensemble velocity vanishes. Some additional arguments show, however, that highly symmetrical ($\widehat{P}$-even) objects exhibit no net propulsion while individual less symmetrical ($\widehat{C}\widehat{P}$-even) propellers do propel. Particular magnetization orientation, rendering the shape $\widehat{C}\widehat{P}$-odd, yields unidirectional motion typically associated with chiral structures, such as helices. If instead of a structure with a permanent dipole we consider a polarizable object, some of the arguments have to be modified. For instance, we demonstrate a truly achiral ($\widehat{P}$- and $\widehat{C}\widehat{P}$-even) planar shape with an induced electric dipole that can propel by electro-rotation. We thereby show that chirality is not essential for propulsion due to rotation-translation coupling at low Reynolds number.

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link (url) DOI Project Page [BibTex]

2018

pf Sachs, J., Morozov, K. I., Kenneth, O., Qiu, T., Segreto, N., Fischer, P., Leshansky, A. M. Role of symmetry in driven propulsion at low Reynolds number Phys. Rev. E, 98(6):063105, American Physical Society, December 2018 (article)

link (url) DOI Project Page [BibTex]

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Deep Reinforcement Learning for Event-Triggered Control

Baumann, D., Zhu, J., Martius, G., Trimpe, S.

In Proceedings of the 57th IEEE International Conference on Decision and Control (CDC), pages: 943-950, 57th IEEE International Conference on Decision and Control (CDC), December 2018 (inproceedings)

al ics

arXiv PDF DOI Project Page Project Page [BibTex]

al ics Baumann, D., Zhu, J., Martius, G., Trimpe, S. Deep Reinforcement Learning for Event-Triggered Control In Proceedings of the 57th IEEE International Conference on Decision and Control (CDC), pages: 943-950, 57th IEEE International Conference on Decision and Control (CDC), December 2018 (inproceedings)

arXiv PDF DOI Project Page Project Page [BibTex]

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Efficient Encoding of Dynamical Systems through Local Approximations

Solowjow, F., Mehrjou, A., Schölkopf, B., Trimpe, S.

In Proceedings of the 57th IEEE International Conference on Decision and Control (CDC), pages: 6073 - 6079 , Miami, Fl, USA, December 2018 (inproceedings)

ei ics

arXiv PDF DOI Project Page [BibTex]

ei ics Solowjow, F., Mehrjou, A., Schölkopf, B., Trimpe, S. Efficient Encoding of Dynamical Systems through Local Approximations In Proceedings of the 57th IEEE International Conference on Decision and Control (CDC), pages: 6073 - 6079 , Miami, Fl, USA, December 2018 (inproceedings)

arXiv PDF DOI Project Page [BibTex]

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Optical and Thermophoretic Control of Janus Nanopen Injection into Living Cells

Maier, C. M., Huergo, M. A., Milosevic, S., Pernpeintner, C., Li, M., Singh, D. P., Walker, D., Fischer, P., Feldmann, J., Lohmüller, T.

Nano Letters, 18, pages: 7935–7941, November 2018 (article) Accepted

Abstract
Devising strategies for the controlled injection of functional nanoparticles and reagents into living cells paves the way for novel applications in nanosurgery, sensing, and drug delivery. Here, we demonstrate the light-controlled guiding and injection of plasmonic Janus nanopens into living cells. The pens are made of a gold nanoparticle attached to a dielectric alumina shaft. Balancing optical and thermophoretic forces in an optical tweezer allows single Janus nanopens to be trapped and positioned on the surface of living cells. While the optical injection process involves strong heating of the plasmonic side, the temperature of the alumina stays significantly lower, thus allowing the functionalization with fluorescently labeled, single-stranded DNA and, hence, the spatially controlled injection of genetic material with an untethered nanocarrier.

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link (url) DOI [BibTex]

pf Maier, C. M., Huergo, M. A., Milosevic, S., Pernpeintner, C., Li, M., Singh, D. P., Walker, D., Fischer, P., Feldmann, J., Lohmüller, T. Optical and Thermophoretic Control of Janus Nanopen Injection into Living Cells Nano Letters, 18, pages: 7935–7941, November 2018 (article) Accepted

link (url) DOI [BibTex]

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A swarm of slippery micropropellers penetrates the vitreous body of the eye

Wu, Z., Troll, J., Jeong, H. H., Wei, Q., Stang, M., Ziemssen, F., Wang, Z., Dong, M., Schnichels, S., Qiu, T., Fischer, P.

Science Advances, 4(11):eaat4388, November 2018 (article)

Abstract
The intravitreal delivery of therapeutic agents promises major benefits in the field of ocular medicine. Traditional delivery methods rely on the random, passive diffusion of molecules, which do not allow for the rapid delivery of a concentrated cargo to a defined region at the posterior pole of the eye. The use of particles promises targeted delivery but faces the challenge that most tissues including the vitreous have a tight macromolecular matrix that acts as a barrier and prevents its penetration. Here, we demonstrate novel intravitreal delivery microvehicles slippery micropropellers that can be actively propelled through the vitreous humor to reach the retina. The propulsion is achieved by helical magnetic micropropellers that have a liquid layer coating to minimize adhesion to the surrounding biopolymeric network. The submicrometer diameter of the propellers enables the penetration of the biopolymeric network and the propulsion through the porcine vitreous body of the eye over centimeter distances. Clinical optical coherence tomography is used to monitor the movement of the propellers and confirm their arrival on the retina near the optic disc. Overcoming the adhesion forces and actively navigating a swarm of micropropellers in the dense vitreous humor promise practical applications in ophthalmology.

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Video: Nanorobots propel through the eye link (url) DOI [BibTex]

pf Wu, Z., Troll, J., Jeong, H. H., Wei, Q., Stang, M., Ziemssen, F., Wang, Z., Dong, M., Schnichels, S., Qiu, T., Fischer, P. A swarm of slippery micropropellers penetrates the vitreous body of the eye Science Advances, 4(11):eaat4388, November 2018 (article)

Video: Nanorobots propel through the eye link (url) DOI [BibTex]

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Depth Control of Underwater Robots using Sliding Modes and Gaussian Process Regression

Lima, G. S., Bessa, W. M., Trimpe, S.

In Proceeding of the 15th Latin American Robotics Symposium, João Pessoa, Brazil, 15th Latin American Robotics Symposium, November 2018 (inproceedings)

Abstract
The development of accurate control systems for underwater robotic vehicles relies on the adequate compensation for hydrodynamic effects. In this work, a new robust control scheme is presented for remotely operated underwater vehicles. In order to meet both robustness and tracking requirements, sliding mode control is combined with Gaussian process regression. The convergence properties of the closed-loop signals are analytically proven. Numerical results confirm the stronger improved performance of the proposed control scheme.

ics

[BibTex]

ics Lima, G. S., Bessa, W. M., Trimpe, S. Depth Control of Underwater Robots using Sliding Modes and Gaussian Process Regression In Proceeding of the 15th Latin American Robotics Symposium, João Pessoa, Brazil, 15th Latin American Robotics Symposium, November 2018 (inproceedings)

[BibTex]

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Gait learning for soft microrobots controlled by light fields

Rohr, A. V., Trimpe, S., Marco, A., Fischer, P., Palagi, S.

In International Conference on Intelligent Robots and Systems (IROS) 2018, pages: 6199-6206, International Conference on Intelligent Robots and Systems 2018, October 2018 (inproceedings)

Abstract
Soft microrobots based on photoresponsive materials and controlled by light fields can generate a variety of different gaits. This inherent flexibility can be exploited to maximize their locomotion performance in a given environment and used to adapt them to changing environments. However, because of the lack of accurate locomotion models, and given the intrinsic variability among microrobots, analytical control design is not possible. Common data-driven approaches, on the other hand, require running prohibitive numbers of experiments and lead to very sample-specific results. Here we propose a probabilistic learning approach for light-controlled soft microrobots based on Bayesian Optimization (BO) and Gaussian Processes (GPs). The proposed approach results in a learning scheme that is highly data-efficient, enabling gait optimization with a limited experimental budget, and robust against differences among microrobot samples. These features are obtained by designing the learning scheme through the comparison of different GP priors and BO settings on a semisynthetic data set. The developed learning scheme is validated in microrobot experiments, resulting in a 115% improvement in a microrobot’s locomotion performance with an experimental budget of only 20 tests. These encouraging results lead the way toward self-adaptive microrobotic systems based on lightcontrolled soft microrobots and probabilistic learning control.

ics pf

arXiv IEEE Xplore DOI Project Page [BibTex]

ics pf Rohr, A. V., Trimpe, S., Marco, A., Fischer, P., Palagi, S. Gait learning for soft microrobots controlled by light fields In International Conference on Intelligent Robots and Systems (IROS) 2018, pages: 6199-6206, International Conference on Intelligent Robots and Systems 2018, October 2018 (inproceedings)

arXiv IEEE Xplore DOI Project Page [BibTex]

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Nanoscale robotic agents in biological fluids and tissues

Palagi, S., Walker, D. Q. T., Fischer, P.

In The Encyclopedia of Medical Robotics, 2, pages: 19-42, 2, (Editors: Desai, J. P. and Ferreira, A.), World Scientific, October 2018 (inbook)

Abstract
Nanorobots are untethered structures of sub-micron size that can be controlled in a non-trivial way. Such nanoscale robotic agents are envisioned to revolutionize medicine by enabling minimally invasive diagnostic and therapeutic procedures. To be useful, nanorobots must be operated in complex biological fluids and tissues, which are often difficult to penetrate. In this chapter, we first discuss potential medical applications of motile nanorobots. We briefly present the challenges related to swimming at such small scales and we survey the rheological properties of some biological fluids and tissues. We then review recent experimental results in the development of nanorobots and in particular their design, fabrication, actuation, and propulsion in complex biological fluids and tissues. Recent work shows that their nanoscale dimension is a clear asset for operation in biological tissues, since many biological tissues consist of networks of macromolecules that prevent the passage of larger micron-scale structures, but contain dynamic pores through which nanorobots can move.

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link (url) DOI [BibTex]

pf Palagi, S., Walker, D. Q. T., Fischer, P. Nanoscale robotic agents in biological fluids and tissues In The Encyclopedia of Medical Robotics, 2, pages: 19-42, 2, (Editors: Desai, J. P. and Ferreira, A.), World Scientific, October 2018 (inbook)

link (url) DOI [BibTex]

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Fast spatial scanning of 3D ultrasound fields via thermography

Melde, K., Qiu, T., Fischer, P.

Applied Physics Letters, 113(13):133503, September 2018 (article)

Abstract
We propose and demonstrate a thermographic method that allows rapid scanning of ultrasound fields in a volume to yield 3D maps of the sound intensity. A thin sound-absorbing membrane is continuously translated through a volume of interest while a thermal camera records the evolution of its surface temperature. The temperature rise is a function of the absorbed sound intensity, such that the thermal image sequence can be combined to reveal the sound intensity distribution in the traversed volume. We demonstrate the mapping of ultrasound fields, which is several orders of magnitude faster than scanning with a hydrophone. Our results are in very good agreement with theoretical simulations.

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link (url) DOI Project Page [BibTex]

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Diffusion Measurements of Swimming Enzymes with Fluorescence Correlation Spectroscopy

Günther, J., Börsch, M., Fischer, P.

Accounts of Chemical Research, 51(9):1911-1920, August 2018 (article)

Abstract
Self-propelled chemical motors are chemically powered micro- or nanosized swimmers. The energy required for these motors’ active motion derives from catalytic chemical reactions and the transformation of a fuel dissolved in the solution. While self-propulsion is now well established for larger particles, it is still unclear if enzymes, nature’s nanometer-sized catalysts, are potentially also self-powered nanomotors. Because of its small size, any increase in an enzyme’s diffusion due to active self-propulsion must be observed on top of the enzyme’s passive Brownian motion, which dominates at this scale. Fluorescence correlation spectroscopy (FCS) is a sensitive method to quantify the diffusion properties of single fluorescently labeled molecules in solution. FCS experiments have shown a general increase in the diffusion constant of a number of enzymes when the enzyme is catalytically active. Diffusion enhancements after addition of the enzyme’s substrate (and sometimes its inhibitor) of up to 80\% have been reported, which is at least 1 order of magnitude higher than what theory would predict. However, many factors contribute to the FCS signal and in particular the shape of the autocorrelation function, which underlies diffusion measurements by fluorescence correlation spectroscopy. These effects need to be considered to establish if and by how much the catalytic activity changes an enzyme’s diffusion.We carefully review phenomena that can play a role in FCS experiments and the determination of enzyme diffusion, including the dissociation of enzyme oligomers upon interaction with the substrate, surface binding of the enzyme to glass during the experiment, conformational changes upon binding, and quenching of the fluorophore. We show that these effects can cause changes in the FCS signal that behave similar to an increase in diffusion. However, in the case of the enzymes F1-ATPase and alkaline phosphatase, we demonstrate that there is no measurable increase in enzyme diffusion. Rather, dissociation and conformational changes account for the changes in the FCS signal in the former and fluorophore quenching in the latter. Within the experimental accuracy of our FCS measurements, we do not observe any change in diffusion due to activity for the enzymes we have investigated.We suggest useful control experiments and additional tests for future FCS experiments that should help establish if the observed diffusion enhancement is real or if it is due to an experimental or data analysis artifact. We show that fluorescence lifetime and mean intensity measurements are essential in order to identify the nature of the observed changes in the autocorrelation function. While it is clear from theory that chemically active enzymes should also act as self-propelled nanomotors, our FCS measurements show that the associated increase in diffusion is much smaller than previously reported. Further experiments are needed to quantify the contribution of the enzymes’ catalytic activity to their self-propulsion. We hope that our findings help to establish a useful protocol for future FCS studies in this field and help establish by how much the diffusion of an enzyme is enhanced through catalytic activity.

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link (url) DOI [BibTex]

pf Günther, J., Börsch, M., Fischer, P. Diffusion Measurements of Swimming Enzymes with Fluorescence Correlation Spectroscopy Accounts of Chemical Research, 51(9):1911-1920, August 2018 (article)

link (url) DOI [BibTex]

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Uphill production of dihydrogen by enzymatic oxidation of glucose without an external energy source

Suraniti, E., Merzeau, P., Roche, J., Gounel, S., Mark, A. G., Fischer, P., Mano, N., Kuhn, A.

Nature Communications, 9(1):3229, August 2018 (article)

Abstract
Chemical systems do not allow the coupling of energy from several simple reactions to drive a subsequent reaction, which takes place in the same medium and leads to a product with a higher energy than the one released during the first reaction. Gibbs energy considerations thus are not favorable to drive e.g., water splitting by the direct oxidation of glucose as a model reaction. Here, we show that it is nevertheless possible to carry out such an energetically uphill reaction, if the electrons released in the oxidation reaction are temporarily stored in an electromagnetic system, which is then used to raise the electrons' potential energy so that they can power the electrolysis of water in a second step. We thereby demonstrate the general concept that lower energy delivering chemical reactions can be used to enable the formation of higher energy consuming reaction products in a closed system.

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link (url) DOI [BibTex]

pf Suraniti, E., Merzeau, P., Roche, J., Gounel, S., Mark, A. G., Fischer, P., Mano, N., Kuhn, A. Uphill production of dihydrogen by enzymatic oxidation of glucose without an external energy source Nature Communications, 9(1):3229, August 2018 (article)

link (url) DOI [BibTex]

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Chemical micromotors self-assemble and self-propel by spontaneous symmetry breaking

Yu, T., Chuphal, P., Thakur, S., Reigh, S. Y., Singh, D. P., Fischer, P.

Chem. Comm., 54, pages: 11933-11936, August 2018 (article)

Abstract
Self-propelling chemical motors have thus far required the fabrication of Janus particles with an asymmetric catalyst distribution. Here, we demonstrate that simple, isotropic colloids can spontaneously assemble to yield dimer motors that self-propel. In a mixture of isotropic titanium dioxide colloids with photo-chemical catalytic activity and passive silica colloids, light illumination causes diffusiophoretic attractions between the active and passive particles and leads to the formation of dimers. The dimers constitute a symmetry-broken motor, whose dynamics can be fully controlled by the illumination conditions. Computer simulations reproduce the dynamics of the colloids and are in good agreement with experiments. The current work presents a simple route to obtain large numbers of self-propelling chemical motors from a dispersion of spherically symmetric colloids through spontaneous symmetry breaking.

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link (url) DOI [BibTex]

pf Yu, T., Chuphal, P., Thakur, S., Reigh, S. Y., Singh, D. P., Fischer, P. Chemical micromotors self-assemble and self-propel by spontaneous symmetry breaking Chem. Comm., 54, pages: 11933-11936, August 2018 (article)

link (url) DOI [BibTex]

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Learning-Based Robust Model Predictive Control with State-Dependent Uncertainty

Soloperto, R., Müller, M. A., Trimpe, S., Allgöwer, F.

In Proceedings of the IFAC Conference on Nonlinear Model Predictive Control (NMPC), Madison, Wisconsin, USA, 6th IFAC Conference on Nonlinear Model Predictive Control, August 2018 (inproceedings)

ics

PDF [BibTex]

ics Soloperto, R., Müller, M. A., Trimpe, S., Allgöwer, F. Learning-Based Robust Model Predictive Control with State-Dependent Uncertainty In Proceedings of the IFAC Conference on Nonlinear Model Predictive Control (NMPC), Madison, Wisconsin, USA, 6th IFAC Conference on Nonlinear Model Predictive Control, August 2018 (inproceedings)

PDF [BibTex]

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A machine from machines

Fischer, P.

Nature Physics, 14, pages: 1072–1073, July 2018 (misc)

Abstract
Building spinning microrotors that self-assemble and synchronize to form a gear sounds like an impossible feat. However, it has now been achieved using only a single type of building block -- a colloid that self-propels.

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link (url) DOI [BibTex]

pf Fischer, P. A machine from machines Nature Physics, 14, pages: 1072–1073, July 2018 (misc)

link (url) DOI [BibTex]

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Chemotaxis of Active Janus Nanoparticles

Popescu, M. N., Uspal, W. E., Bechinger, C., Fischer, P.

Nano Letters, 18(9):5345–5349, July 2018 (article)

Abstract
While colloids and molecules in solution exhibit passive Brownian motion, particles that are partially covered with a catalyst, which promotes the transformation of a fuel dissolved in the solution, can actively move. These active Janus particles are known as “chemical nanomotors” or self-propelling “swimmers” and have been realized with a range of catalysts, sizes, and particle geometries. Because their active translation depends on the fuel concentration, one expects that active colloidal particles should also be able to swim toward a fuel source. Synthesizing and engineering nanoparticles with distinct chemotactic properties may enable important developments, such as particles that can autonomously swim along a pH gradient toward a tumor. Chemotaxis requires that the particles possess an active coupling of their orientation to a chemical gradient. In this Perspective we provide a simple, intuitive description of the underlying mechanisms for chemotaxis, as well as the means to analyze and classify active particles that can show positive or negative chemotaxis. The classification provides guidance for engineering a specific response and is a useful organizing framework for the quantitative analysis and modeling of chemotactic behaviors. Chemotaxis is emerging as an important focus area in the field of active colloids and promises a number of fascinating applications for nanoparticles and particle-based delivery.

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link (url) DOI [BibTex]

pf Popescu, M. N., Uspal, W. E., Bechinger, C., Fischer, P. Chemotaxis of Active Janus Nanoparticles Nano Letters, 18(9):5345–5349, July 2018 (article)

link (url) DOI [BibTex]

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Learning an Approximate Model Predictive Controller with Guarantees

Hertneck, M., Koehler, J., Trimpe, S., Allgöwer, F.

IEEE Control Systems Letters, 2(3):543-548, July 2018 (article)

Abstract
A supervised learning framework is proposed to approximate a model predictive controller (MPC) with reduced computational complexity and guarantees on stability and constraint satisfaction. The framework can be used for a wide class of nonlinear systems. Any standard supervised learning technique (e.g. neural networks) can be employed to approximate the MPC from samples. In order to obtain closed-loop guarantees for the learned MPC, a robust MPC design is combined with statistical learning bounds. The MPC design ensures robustness to inaccurate inputs within given bounds, and Hoeffding’s Inequality is used to validate that the learned MPC satisfies these bounds with high confidence. The result is a closed-loop statistical guarantee on stability and constraint satisfaction for the learned MPC. The proposed learning-based MPC framework is illustrated on a nonlinear benchmark problem, for which we learn a neural network controller with guarantees.

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arXiv PDF DOI [BibTex]

ics Hertneck, M., Koehler, J., Trimpe, S., Allgöwer, F. Learning an Approximate Model Predictive Controller with Guarantees IEEE Control Systems Letters, 2(3):543-548, July 2018 (article)

arXiv PDF DOI [BibTex]

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Probabilistic Recurrent State-Space Models

Doerr, A., Daniel, C., Schiegg, M., Nguyen-Tuong, D., Schaal, S., Toussaint, M., Trimpe, S.

In Proceedings of the International Conference on Machine Learning (ICML), International Conference on Machine Learning (ICML), July 2018 (inproceedings)

Abstract
State-space models (SSMs) are a highly expressive model class for learning patterns in time series data and for system identification. Deterministic versions of SSMs (e.g., LSTMs) proved extremely successful in modeling complex time-series data. Fully probabilistic SSMs, however, unfortunately often prove hard to train, even for smaller problems. To overcome this limitation, we propose a scalable initialization and training algorithm based on doubly stochastic variational inference and Gaussian processes. In the variational approximation we propose in contrast to related approaches to fully capture the latent state temporal correlations to allow for robust training.

am ics

arXiv pdf Project Page [BibTex]

am ics Doerr, A., Daniel, C., Schiegg, M., Nguyen-Tuong, D., Schaal, S., Toussaint, M., Trimpe, S. Probabilistic Recurrent State-Space Models In Proceedings of the International Conference on Machine Learning (ICML), International Conference on Machine Learning (ICML), July 2018 (inproceedings)

arXiv pdf Project Page [BibTex]

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Event-triggered Learning for Resource-efficient Networked Control

Solowjow, F., Baumann, D., Garcke, J., Trimpe, S.

In Proceedings of the American Control Conference (ACC), pages: 6506 - 6512, American Control Conference, June 2018 (inproceedings)

ics

arXiv PDF DOI Project Page [BibTex]

ics Solowjow, F., Baumann, D., Garcke, J., Trimpe, S. Event-triggered Learning for Resource-efficient Networked Control In Proceedings of the American Control Conference (ACC), pages: 6506 - 6512, American Control Conference, June 2018 (inproceedings)

arXiv PDF DOI Project Page [BibTex]

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Colloidal Chemical Nanomotors

Alarcon-Correa, M.

Colloidal Chemical Nanomotors, pages: 150, Cuvillier Verlag, MPI-IS , June 2018 (phdthesis)

Abstract
Synthetic sophisticated nanostructures represent a fundamental building block for the development of nanotechnology. The fabrication of nanoparticles complex in structure and material composition is key to build nanomachines that can operate as man-made nanoscale motors, which autonomously convert external energy into motion. To achieve this, asymmetric nanoparticles were fabricated combining a physical vapor deposition technique known as NanoGLAD and wet chemical synthesis. This thesis primarily concerns three complex colloidal systems that have been developed: i)Hollow nanocup inclusion complexes that have a single Au nanoparticle in their pocket. The Au particle can be released with an external trigger. ii)The smallest self-propelling nanocolloids that have been made to date, which give rise to a local concentration gradient that causes enhanced diffusion of the particles. iii)Enzyme-powered pumps that have been assembled using bacteriophages as biological nanoscaffolds. This construct also can be used for enzyme recovery after heterogeneous catalysis.

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[BibTex]

pf Alarcon-Correa, M. Colloidal Chemical Nanomotors Colloidal Chemical Nanomotors, pages: 150, Cuvillier Verlag, MPI-IS , June 2018 (phdthesis)

[BibTex]

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Bioinspired microrobots

Palagi, S., Fischer, P.

Nature Reviews Materials, 3, pages: 113–124, May 2018 (article)

Abstract
Microorganisms can move in complex media, respond to the environment and self-organize. The field of microrobotics strives to achieve these functions in mobile robotic systems of sub-millimetre size. However, miniaturization of traditional robots and their control systems to the microscale is not a viable approach. A promising alternative strategy in developing microrobots is to implement sensing, actuation and control directly in the materials, thereby mimicking biological matter. In this Review, we discuss design principles and materials for the implementation of robotic functionalities in microrobots. We examine different biological locomotion strategies, and we discuss how they can be artificially recreated in magnetic microrobots and how soft materials improve control and performance. We show that smart, stimuli-responsive materials can act as on-board sensors and actuators and that ‘active matter’ enables autonomous motion, navigation and collective behaviours. Finally, we provide a critical outlook for the field of microrobotics and highlight the challenges that need to be overcome to realize sophisticated microrobots, which one day might rival biological machines.

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link (url) DOI [BibTex]

pf Palagi, S., Fischer, P. Bioinspired microrobots Nature Reviews Materials, 3, pages: 113–124, May 2018 (article)

link (url) DOI [BibTex]

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Soft Miniaturized Linear Actuators Wirelessly Powered by Rotating Permanent Magnets

Qiu, T., Palagi, S., Sachs, J., Fischer, P.

In 2018 IEEE International Conference on Robotics and Automation (ICRA), pages: 3595-3600, May 2018 (inproceedings)

Abstract
Wireless actuation by magnetic fields allows for the operation of untethered miniaturized devices, e.g. in biomedical applications. Nevertheless, generating large controlled forces over relatively large distances is challenging. Magnetic torques are easier to generate and control, but they are not always suitable for the tasks at hand. Moreover, strong magnetic fields are required to generate a sufficient torque, which are difficult to achieve with electromagnets. Here, we demonstrate a soft miniaturized actuator that transforms an externally applied magnetic torque into a controlled linear force. We report the design, fabrication and characterization of both the actuator and the magnetic field generator. We show that the magnet assembly, which is based on a set of rotating permanent magnets, can generate strong controlled oscillating fields over a relatively large workspace. The actuator, which is 3D-printed, can lift a load of more than 40 times its weight. Finally, we show that the actuator can be further miniaturized, paving the way towards strong, wirelessly powered microactuators.

pf

link (url) DOI [BibTex]

pf Qiu, T., Palagi, S., Sachs, J., Fischer, P. Soft Miniaturized Linear Actuators Wirelessly Powered by Rotating Permanent Magnets In 2018 IEEE International Conference on Robotics and Automation (ICRA), pages: 3595-3600, May 2018 (inproceedings)

link (url) DOI [BibTex]

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Graphene-silver hybrid devices for sensitive photodetection in the ultraviolet

Paria, D., Jeong, H. H., Vadakkumbatt, V., Deshpande, P., Fischer, P., Ghosh, A., Ghosh, A.

Nanoscale, 10, pages: 7685-7693, April 2018 (article)

Abstract
The weak light-matter interaction in graphene can be enhanced with a number of strategies, among which sensitization with plasmonic nanostructures is particularly attractive. This has resulted in the development of graphene-plasmonic hybrid systems with strongly enhanced photodetection efficiencies in the visible and the IR, but none in the UV. Here, we describe a silver nanoparticle-graphene stacked optoelectronic device that shows strong enhancement of its photoresponse across the entire UV spectrum. The device fabrication strategy is scalable and modular. Self-assembly techniques are combined with physical shadow growth techniques to fabricate a regular large-area array of 50 nm silver nanoparticles onto which CVD graphene is transferred. The presence of the silver nanoparticles resulted in a plasmonically enhanced photoresponse as high as 3.2 A W-1 in the wavelength range from 330 nm to 450 nm. At lower wavelengths, close to the Van Hove singularity of the density of states in graphene, we measured an even higher responsivity of 14.5 A W-1 at 280 nm, which corresponds to a more than 10 000-fold enhancement over the photoresponse of native graphene.

pf

link (url) DOI [BibTex]

pf Paria, D., Jeong, H. H., Vadakkumbatt, V., Deshpande, P., Fischer, P., Ghosh, A., Ghosh, A. Graphene-silver hybrid devices for sensitive photodetection in the ultraviolet Nanoscale, 10, pages: 7685-7693, April 2018 (article)

link (url) DOI [BibTex]

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Nanoparticles on the move for medicine

Fischer, P.

Physics World Focus on Nanotechnology, pages: 26028, (Editors: Margaret Harris), IOP Publishing Ltd and individual contributors, April 2018 (article)

Abstract
Peer Fischer outlines the prospects for creating “nanoswimmers” that can be steered through the body to deliver drugs directly to their targets Molecules don’t move very fast on their own. If they had to rely solely on diffusion – a slow and inefficient process linked to the Brownian motion of small particles and molecules in solution – then a protein mole­cule, for instance, would take around three weeks to travel a single centimetre down a nerve fibre. This is why active transport mechanisms exist in cells and in the human body: without them, all the processes of life would happen at a pace that would make snails look speedy.

pf

link (url) [BibTex]

pf Fischer, P. Nanoparticles on the move for medicine Physics World Focus on Nanotechnology, pages: 26028, (Editors: Margaret Harris), IOP Publishing Ltd and individual contributors, April 2018 (article)

link (url) [BibTex]

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Poster Abstract: Toward Fast Closed-loop Control over Multi-hop Low-power Wireless Networks

Mager, F., Baumann, D., Trimpe, S., Zimmerling, M.

Proceedings of the 17th ACM/IEEE Conference on Information Processing in Sensor Networks (IPSN), pages: 158-159, Porto, Portugal, April 2018 (poster)

ics

DOI Project Page [BibTex]

ics Mager, F., Baumann, D., Trimpe, S., Zimmerling, M. Poster Abstract: Toward Fast Closed-loop Control over Multi-hop Low-power Wireless Networks Proceedings of the 17th ACM/IEEE Conference on Information Processing in Sensor Networks (IPSN), pages: 158-159, Porto, Portugal, April 2018 (poster)

DOI Project Page [BibTex]

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Evaluating Low-Power Wireless Cyber-Physical Systems

Baumann, D., Mager, F., Singh, H., Zimmerling, M., Trimpe, S.

In Proceedings of the IEEE Workshop on Benchmarking Cyber-Physical Networks and Systems (CPSBench), pages: 13-18, IEEE Workshop on Benchmarking Cyber-Physical Networks and Systems (CPSBench), April 2018 (inproceedings)

ics

arXiv PDF DOI Project Page [BibTex]

ics Baumann, D., Mager, F., Singh, H., Zimmerling, M., Trimpe, S. Evaluating Low-Power Wireless Cyber-Physical Systems In Proceedings of the IEEE Workshop on Benchmarking Cyber-Physical Networks and Systems (CPSBench), pages: 13-18, IEEE Workshop on Benchmarking Cyber-Physical Networks and Systems (CPSBench), April 2018 (inproceedings)

arXiv PDF DOI Project Page [BibTex]

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Photogravitactic Microswimmers

Singh, D. P., Uspal, W. E., Popescu, M. N., Wilson, L. G., Fischer, P.

Adv. Func. Mat., 28, pages: 1706660, Febuary 2018 (article)

Abstract
Abstract Phototactic microorganisms are commonly observed to respond to natural sunlight by swimming upward against gravity. This study demonstrates that synthetic photochemically active microswimmers can also swim against gravity. The particles initially sediment and, when illuminated at low light intensities exhibit wall‐bound states of motion near the bottom surface. Upon increasing the intensity of light, the artificial swimmers lift off from the wall and swim against gravity and away from the light source. This motion in the bulk has been further confirmed using holographic microscopy. A theoretical model is presented within the framework of self‐diffusiophoresis, which allows to unequivocally identify the photochemical activity and the phototactic response as key mechanisms in the observed phenomenology. Since the lift‐off threshold intensity depends on the particle size, it can be exploited to selectively address particles with the same density from a polydisperse mixture of active particles and move them in or out of the boundary region. This study provides a simple design strategy to fabricate artificial microswimmers whose two‐ or three‐dimensional swimming behavior can be controlled with light.

pf

link (url) DOI [BibTex]

pf Singh, D. P., Uspal, W. E., Popescu, M. N., Wilson, L. G., Fischer, P. Photogravitactic Microswimmers Adv. Func. Mat., 28, pages: 1706660, Febuary 2018 (article)

link (url) DOI [BibTex]

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Chiral Plasmonic Hydrogen Sensors

Matuschek, M., Singh, D. P., Hyeon-Ho, J., Nesterov, M., Weiss, T., Fischer, P., Neubrech, F., Na Liu, L.

Small, 14(7):1702990, Febuary 2018 (article)

Abstract
In this article, a chiral plasmonic hydrogen‐sensing platform using palladium‐based nanohelices is demonstrated. Such 3D chiral nanostructures fabricated by nanoglancing angle deposition exhibit strong circular dichroism both experimentally and theoretically. The chiroptical properties of the palladium nanohelices are altered upon hydrogen uptake and sensitively depend on the hydrogen concentration. Such properties are well suited for remote and spark‐free hydrogen sensing in the flammable range. Hysteresis is reduced, when an increasing amount of gold is utilized in the palladium‐gold hybrid helices. As a result, the linearity of the circular dichroism in response to hydrogen is significantly improved. The chiral plasmonic sensor scheme is of potential interest for hydrogen‐sensing applications, where good linearity and high sensitivity are required.

pf

link (url) DOI [BibTex]

pf Matuschek, M., Singh, D. P., Hyeon-Ho, J., Nesterov, M., Weiss, T., Fischer, P., Neubrech, F., Na Liu, L. Chiral Plasmonic Hydrogen Sensors Small, 14(7):1702990, Febuary 2018 (article)

link (url) DOI [BibTex]

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Acoustic Fabrication via the Assembly and Fusion of Particles

Melde, K., Choi, E., Wu, Z., Palagi, S., Qiu, T., Fischer, P.

Advanced Materials, 30(3):1704507, January 2018 (article)

Abstract
Acoustic assembly promises a route toward rapid parallel fabrication of whole objects directly from solution. This study reports the contact-free and maskless assembly, and fixing of silicone particles into arbitrary 2D shapes using ultrasound fields. Ultrasound passes through an acoustic hologram to form a target image. The particles assemble from a suspension along lines of high pressure in the image due to acoustic radiation forces and are then fixed (crosslinked) in a UV-triggered reaction. For this, the particles are loaded with a photoinitiator by solvent-induced swelling. This localizes the reaction and allows the bulk suspension to be reused. The final fabricated parts are mechanically stable and self-supporting.

pf

link (url) DOI Project Page [BibTex]

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Distributed Event-Based State Estimation for Networked Systems: An LMI Approach

Muehlebach, M., Trimpe, S.

IEEE Transactions on Automatic Control, 63(1):269-276, January 2018 (article)

am ics

arXiv (extended version) DOI Project Page [BibTex]

am ics Muehlebach, M., Trimpe, S. Distributed Event-Based State Estimation for Networked Systems: An LMI Approach IEEE Transactions on Automatic Control, 63(1):269-276, January 2018 (article)

arXiv (extended version) DOI Project Page [BibTex]

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Nanorobots propel through the eye

Zhiguang Wu, J. T. H. J. Q. W. M. S. F. Z. Z. W. M. D. S. S. T. Q. P. F.

Max Planck Society, 2018 (mpi_year_book)

Abstract
Scientists at the Max Planck Institute for Intelligent Systems in Stuttgart developed specially coated nanometer-sized robots that could be moved actively through dense tissue like the vitreous of the eye. So far, the transport of such nano-vehicles has only been demonstrated in model systems or biological fluids, but not in real tissue. Our work constitutes one step further towards nanorobots becoming minimally-invasive tools for precisely delivering medicine to where it is needed.

pf

link (url) [BibTex]

2015

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Enzymatically active biomimetic micropropellers for the penetration of mucin gels

Walker (Schamel), D., Käsdorf, B. T., Jeong, H. H., Lieleg, O., Fischer, P.

Science Advances, 1(11):e1500501, December 2015 (article)

Abstract
In the body, mucus provides an important defense mechanism by limiting the penetration of pathogens. It is therefore also a major obstacle for the efficient delivery of particle-based drug carriers. The acidic stomach lining in particular is difficult to overcome because mucin glycoproteins form viscoelastic gels under acidic conditions. The bacterium Helicobacter pylori has developed a strategy to overcome the mucus barrier by producing the enzyme urease, which locally raises the pH and consequently liquefies the mucus. This allows the bacteria to swim through mucus and to reach the epithelial surface. We present an artificial system of reactive magnetic micropropellers that mimic this strategy to move through gastric mucin gels by making use of surface-immobilized urease. The results demonstrate the validity of this biomimetic approach to penetrate biological gels, and show that externally propelled microstructures can actively and reversibly manipulate the physical state of their surroundings, suggesting that such particles could potentially penetrate native mucus.

pf

link (url) DOI [BibTex]

2015

pf Walker (Schamel), D., Käsdorf, B. T., Jeong, H. H., Lieleg, O., Fischer, P. Enzymatically active biomimetic micropropellers for the penetration of mucin gels Science Advances, 1(11):e1500501, December 2015 (article)

link (url) DOI [BibTex]

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Distributed Event-based State Estimation

Trimpe, S.

Max Planck Institute for Intelligent Systems, November 2015 (techreport)

Abstract
An event-based state estimation approach for reducing communication in a networked control system is proposed. Multiple distributed sensor-actuator-agents observe a dynamic process and sporadically exchange their measurements and inputs over a bus network. Based on these data, each agent estimates the full state of the dynamic system, which may exhibit arbitrary inter-agent couplings. Local event-based protocols ensure that data is transmitted only when necessary to meet a desired estimation accuracy. This event-based scheme is shown to mimic a centralized Luenberger observer design up to guaranteed bounds, and stability is proven in the sense of bounded estimation errors for bounded disturbances. The stability result extends to the distributed control system that results when the local state estimates are used for distributed feedback control. Simulation results highlight the benefit of the event-based approach over classical periodic ones in reducing communication requirements.

am ics

arXiv [BibTex]

am ics Trimpe, S. Distributed Event-based State Estimation Max Planck Institute for Intelligent Systems, November 2015 (techreport)

arXiv [BibTex]

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Automatic LQR Tuning Based on Gaussian Process Optimization: Early Experimental Results

Marco, A., Hennig, P., Bohg, J., Schaal, S., Trimpe, S.

Machine Learning in Planning and Control of Robot Motion Workshop at the IEEE/RSJ International Conference on Intelligent Robots and Systems (iROS), pages: , , Machine Learning in Planning and Control of Robot Motion Workshop, October 2015 (conference)

Abstract
This paper proposes an automatic controller tuning framework based on linear optimal control combined with Bayesian optimization. With this framework, an initial set of controller gains is automatically improved according to a pre-defined performance objective evaluated from experimental data. The underlying Bayesian optimization algorithm is Entropy Search, which represents the latent objective as a Gaussian process and constructs an explicit belief over the location of the objective minimum. This is used to maximize the information gain from each experimental evaluation. Thus, this framework shall yield improved controllers with fewer evaluations compared to alternative approaches. A seven-degree-of-freedom robot arm balancing an inverted pole is used as the experimental demonstrator. Preliminary results of a low-dimensional tuning problem highlight the method’s potential for automatic controller tuning on robotic platforms.

am ei ics pn

PDF DOI Project Page [BibTex]

am ei ics pn Marco, A., Hennig, P., Bohg, J., Schaal, S., Trimpe, S. Automatic LQR Tuning Based on Gaussian Process Optimization: Early Experimental Results Machine Learning in Planning and Control of Robot Motion Workshop at the IEEE/RSJ International Conference on Intelligent Robots and Systems (iROS), pages: , , Machine Learning in Planning and Control of Robot Motion Workshop, October 2015 (conference)

PDF DOI Project Page [BibTex]

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Gaussian Process Optimization for Self-Tuning Control

Marco, A.

Polytechnic University of Catalonia (BarcelonaTech), October 2015 (mastersthesis)

am ics

PDF Project Page [BibTex]

am ics Marco, A. Gaussian Process Optimization for Self-Tuning Control Polytechnic University of Catalonia (BarcelonaTech), October 2015 (mastersthesis)

PDF Project Page [BibTex]

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The EChemPen: A Guiding Hand To Learn Electrochemical Surface Modifications

Valetaud, M., Loget, G., Roche, J., Hueken, N., Fattah, Z., Badets, V., Fontaine, O., Zigah, D.

J. of Chem. Ed., 92(10):1700-1704, September 2015 (article)

Abstract
The Electrochemical Pen (EChemPen) was developed as an attractive tool for learning electrochemistry. The fabrication, principle, and operation of the EChemPen are simple and can be easily performed by students in practical classes. It is based on a regular fountain pen principle, where the electrolytic solution is dispensed at a tip to locally modify a conductive surface by triggering a localized electrochemical reaction. Three simple model reactions were chosen to demonstrate the versatility of the EChemPen for teaching various electrochemical processes. We describe first the reversible writing/erasing of metal letters, then the electrodeposition of a black conducting polymer "ink", and finally the colorful writings that can be generated by titanium anodization and that can be controlled by the applied potential. These entertaining and didactic experiments are adapted for teaching undergraduate students that start to study electrochemistry by means of surface modification reactions.

pf

DOI [BibTex]

pf Valetaud, M., Loget, G., Roche, J., Hueken, N., Fattah, Z., Badets, V., Fontaine, O., Zigah, D. The EChemPen: A Guiding Hand To Learn Electrochemical Surface Modifications J. of Chem. Ed., 92(10):1700-1704, September 2015 (article)

DOI [BibTex]

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Adaptive and Learning Concepts in Hydraulic Force Control

Doerr, A.

University of Stuttgart, September 2015 (mastersthesis)

am ics

[BibTex]

am ics Doerr, A. Adaptive and Learning Concepts in Hydraulic Force Control University of Stuttgart, September 2015 (mastersthesis)

[BibTex]

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3D-printed Soft Microrobot for Swimming in Biological Fluids

Qiu, T., Palagi, S., Fischer, P.

In Conf. Proc. IEEE Eng. Med. Biol. Soc., pages: 4922-4925, August 2015 (inproceedings)

Abstract
Microscopic artificial swimmers hold the potential to enable novel non-invasive medical procedures. In order to ease their translation towards real biomedical applications, simpler designs as well as cheaper yet more reliable materials and fabrication processes should be adopted, provided that the functionality of the microrobots can be kept. A simple single-hinge design could already enable microswimming in non-Newtonian fluids, which most bodily fluids are. Here, we address the fabrication of such single-hinge microrobots with a 3D-printed soft material. Firstly, a finite element model is developed to investigate the deformability of the 3D-printed microstructure under typical values of the actuating magnetic fields. Then the microstructures are fabricated by direct 3D-printing of a soft material and their swimming performances are evaluated. The speeds achieved with the 3D-printed microrobots are comparable to those obtained in previous work with complex fabrication procedures, thus showing great promise for 3D-printed microrobots to be operated in biological fluids.

pf

link (url) DOI [BibTex]

pf Qiu, T., Palagi, S., Fischer, P. 3D-printed Soft Microrobot for Swimming in Biological Fluids In Conf. Proc. IEEE Eng. Med. Biol. Soc., pages: 4922-4925, August 2015 (inproceedings)

link (url) DOI [BibTex]

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Direct Loss Minimization Inverse Optimal Control

Doerr, A., Ratliff, N., Bohg, J., Toussaint, M., Schaal, S.

In Proceedings of Robotics: Science and Systems, Rome, Italy, Robotics: Science and Systems XI, July 2015 (inproceedings)

Abstract
Inverse Optimal Control (IOC) has strongly impacted the systems engineering process, enabling automated planner tuning through straightforward and intuitive demonstration. The most successful and established applications, though, have been in lower dimensional problems such as navigation planning where exact optimal planning or control is feasible. In higher dimensional systems, such as humanoid robots, research has made substantial progress toward generalizing the ideas to model free or locally optimal settings, but these systems are complicated to the point where demonstration itself can be difficult. Typically, real-world applications are restricted to at best noisy or even partial or incomplete demonstrations that prove cumbersome in existing frameworks. This work derives a very flexible method of IOC based on a form of Structured Prediction known as Direct Loss Minimization. The resulting algorithm is essentially Policy Search on a reward function that rewards similarity to demonstrated behavior (using Covariance Matrix Adaptation (CMA) in our experiments). Our framework blurs the distinction between IOC, other forms of Imitation Learning, and Reinforcement Learning, enabling us to derive simple, versatile, and practical algorithms that blend imitation and reinforcement signals into a unified framework. Our experiments analyze various aspects of its performance and demonstrate its efficacy on conveying preferences for motion shaping and combined reach and grasp quality optimization.

am ics

PDF Video Project Page [BibTex]

am ics Doerr, A., Ratliff, N., Bohg, J., Toussaint, M., Schaal, S. Direct Loss Minimization Inverse Optimal Control In Proceedings of Robotics: Science and Systems, Rome, Italy, Robotics: Science and Systems XI, July 2015 (inproceedings)

PDF Video Project Page [BibTex]

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LMI-Based Synthesis for Distributed Event-Based State Estimation

Muehlebach, M., Trimpe, S.

In Proceedings of the American Control Conference, July 2015 (inproceedings)

Abstract
This paper presents an LMI-based synthesis procedure for distributed event-based state estimation. Multiple agents observe and control a dynamic process by sporadically exchanging data over a broadcast network according to an event-based protocol. In previous work [1], the synthesis of event-based state estimators is based on a centralized design. In that case three different types of communication are required: event-based communication of measurements, periodic reset of all estimates to their joint average, and communication of inputs. The proposed synthesis problem eliminates the communication of inputs as well as the periodic resets (under favorable circumstances) by accounting explicitly for the distributed structure of the control system.

am ics

PDF DOI Project Page [BibTex]

am ics Muehlebach, M., Trimpe, S. LMI-Based Synthesis for Distributed Event-Based State Estimation In Proceedings of the American Control Conference, July 2015 (inproceedings)

PDF DOI Project Page [BibTex]

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Guaranteed H2 Performance in Distributed Event-Based State Estimation

Muehlebach, M., Trimpe, S.

In Proceeding of the First International Conference on Event-based Control, Communication, and Signal Processing, June 2015 (inproceedings)

am ics

PDF DOI Project Page [BibTex]

am ics Muehlebach, M., Trimpe, S. Guaranteed H2 Performance in Distributed Event-Based State Estimation In Proceeding of the First International Conference on Event-based Control, Communication, and Signal Processing, June 2015 (inproceedings)

PDF DOI Project Page [BibTex]

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On the Choice of the Event Trigger in Event-based Estimation

Trimpe, S., Campi, M.

In Proceeding of the First International Conference on Event-based Control, Communication, and Signal Processing, June 2015 (inproceedings)

am ics

PDF DOI Project Page [BibTex]

am ics Trimpe, S., Campi, M. On the Choice of the Event Trigger in Event-based Estimation In Proceeding of the First International Conference on Event-based Control, Communication, and Signal Processing, June 2015 (inproceedings)

PDF DOI Project Page [BibTex]

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Optimal Length of Low Reynolds Number Nanopropellers

Walker (Schamel), D., Kuebler, M., Morozov, K. I., Fischer, P., Leshansky, A. M.

Nano Letters, 15(7):4412-4416, June 2015 (article)

Abstract
Locomotion in fluids at the nanoscale is dominated by viscous drag. One efficient propulsion scheme is to use a weak rotating magnetic field that drives a chiral object. Froth bacterial flagella to artificial drills, the corkscrew is a universally useful chiral shape for propulsion in viscous environments. Externally powered magnetic micro- and nanomotors have been recently developed that allow for precise fuel-free propulsion in complex media. Here, we combine analytical and numerical theory with experiments on nanostructured screw-propellers to show that the optimal length is surprisingly short only about one helical turn, which is shorter than most of the structures in use to date. The results have important implications for the design of artificial actuated nano- and micropropellers and can dramatically reduce fabrication times, while ensuring optimal performance.

pf

DOI [BibTex]

pf Walker (Schamel), D., Kuebler, M., Morozov, K. I., Fischer, P., Leshansky, A. M. Optimal Length of Low Reynolds Number Nanopropellers Nano Letters, 15(7):4412-4416, June 2015 (article)

DOI [BibTex]

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A theoretical study of potentially observable chirality-sensitive NMR effects in molecules

Garbacz, P., Cukras, J., Jaszunski, M.

Phys. Chem. Chem. Phys., 17(35):22642-22651, May 2015 (article)

Abstract
Two recently predicted nuclear magnetic resonance effects, the chirality-induced rotating electric polarization and the oscillating magnetization, are examined for several experimentally available chiral molecules. We discuss in detail the requirements for experimental detection of chirality-sensitive NMR effects of the studied molecules. These requirements are related to two parameters: the shielding polarizability and the antisymmetric part of the nuclear magnetic shielding tensor. The dominant second contribution has been computed for small molecules at the coupled cluster and density functional theory levels. It was found that DFT calculations using the KT2 functional and the aug-cc-pCVTZ basis set adequately reproduce the CCSD(T) values obtained with the same basis set. The largest values of parameters, thus most promising from the experimental point of view, were obtained for the fluorine nuclei in 1,3-difluorocyclopropene and 1,3-diphenyl-2-fluoro-3-trifluoromethylcyclopropene.

pf

DOI [BibTex]

pf Garbacz, P., Cukras, J., Jaszunski, M. A theoretical study of potentially observable chirality-sensitive NMR effects in molecules Phys. Chem. Chem. Phys., 17(35):22642-22651, May 2015 (article)

DOI [BibTex]

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Event-based Estimation and Control for Remote Robot Operation with Reduced Communication

Trimpe, S., Buchli, J.

In Proceedings of the IEEE International Conference on Robotics and Automation, May 2015 (inproceedings)

Abstract
An event-based communication framework for remote operation of a robot via a bandwidth-limited network is proposed. The robot sends state and environment estimation data to the operator, and the operator transmits updated control commands or policies to the robot. Event-based communication protocols are designed to ensure that data is transmitted only when required: the robot sends new estimation data only if this yields a significant information gain at the operator, and the operator transmits an updated control policy only if this comes with a significant improvement in control performance. The developed framework is modular and can be used with any standard estimation and control algorithms. Simulation results of a robotic arm highlight its potential for an efficient use of limited communication resources, for example, in disaster response scenarios such as the DARPA Robotics Challenge.

am ics

PDF DOI Project Page [BibTex]

am ics Trimpe, S., Buchli, J. Event-based Estimation and Control for Remote Robot Operation with Reduced Communication In Proceedings of the IEEE International Conference on Robotics and Automation, May 2015 (inproceedings)

PDF DOI Project Page [BibTex]

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Lernende Roboter

Trimpe, S.

In Jahrbuch der Max-Planck-Gesellschaft, Max Planck Society, May 2015, (popular science article in German) (inbook)

am ics

link (url) [BibTex]

am ics Trimpe, S. Lernende Roboter In Jahrbuch der Max-Planck-Gesellschaft, Max Planck Society, May 2015, (popular science article in German) (inbook)

link (url) [BibTex]

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Dynamic Inclusion Complexes of Metal Nanoparticles Inside Nanocups

Alarcon-Correa, M., Lee, T. C., Fischer, P.

Angew. Chem. Int. Ed., 54(23):6730-6734, May 2015, Featured cover article. (article)

Abstract
Host-guest inclusion complexes are abundant in molecular systems and of fundamental importance in living organisms. Realizing a colloidal analogue of a molecular dynamic inclusion complex is challenging because inorganic nanoparticles (NPs) with a well-defined cavity and portal are difficult to synthesize in high yield and with good structural fidelity. Herein, a generic strategy towards the fabrication of dynamic 1: 1 inclusion complexes of metal nanoparticles inside oxide nanocups with high yield (> 70%) and regiospecificity (> 90%) by means of a reactive double Janus nanoparticle intermediate is reported. Experimental evidence confirms that the inclusion complexes are formed by a kinetically controlled mechanism involving a delicate interplay between bipolar galvanic corrosion and alloying-dealloying oxidation. Release of the NP guest from the nanocups can be efficiently triggered by an external stimulus. Featured cover article.

pf

DOI [BibTex]

pf Alarcon-Correa, M., Lee, T. C., Fischer, P. Dynamic Inclusion Complexes of Metal Nanoparticles Inside Nanocups Angew. Chem. Int. Ed., 54(23):6730-6734, May 2015, Featured cover article. (article)

DOI [BibTex]

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Surface roughness-induced speed increase for active Janus micromotors

Choudhury, U., Soler, L., Gibbs, J. G., Sanchez, S., Fischer, P.

Chem. Comm., 51(41):8660-8663, April 2015 (article)

Abstract
We demonstrate a simple physical fabrication method to control surface roughness of Janus micromotors and fabricate self-propelled active Janus microparticles with rough catalytic platinum surfaces that show a four-fold increase in their propulsion speed compared to conventional Janus particles coated with a smooth Pt layer.

pf

DOI [BibTex]

pf Choudhury, U., Soler, L., Gibbs, J. G., Sanchez, S., Fischer, P. Surface roughness-induced speed increase for active Janus micromotors Chem. Comm., 51(41):8660-8663, April 2015 (article)

DOI [BibTex]

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Active colloidal microdrills

Gibbs, J. G., Fischer, P.

Chem. Comm., 51(20):4192-4195, Febuary 2015 (article)

Abstract
We demonstrate a chemically driven, autonomous catalytic microdrill. An asymmetric distribution of catalyst causes the helical swimmer to twist while it undergoes directed propulsion. A driving torque and hydrodynamic coupling between translation and rotation at low Reynolds number leads to drill-like swimming behaviour.

pf

DOI [BibTex]

pf Gibbs, J. G., Fischer, P. Active colloidal microdrills Chem. Comm., 51(20):4192-4195, Febuary 2015 (article)

DOI [BibTex]

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Policy Search for Imitation Learning

Doerr, A.

University of Stuttgart, January 2015 (thesis)

am ics

link (url) Project Page [BibTex]

am ics Doerr, A. Policy Search for Imitation Learning University of Stuttgart, January 2015 (thesis)

link (url) Project Page [BibTex]

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Selectable Nanopattern Arrays for Nanolithographic Imprint and Etch-Mask Applications

Jeong, H. H., Mark, A. G., Lee, T., Son, K., Chen, W., Alarcon-Correa, M., Kim, I., Schütz, G., Fischer, P.

Adv. Science, 2(7):1500016, 2015, Featured cover article. (article)

Abstract
A parallel nanolithographic patterning method is presented that can be used to obtain arrays of multifunctional nanoparticles. These patterns can simply be converted into a variety of secondary nanopatterns that are useful for nanolithographic imprint, plasmonic, and etch-mask applications.

pf

link (url) DOI [BibTex]

pf Jeong, H. H., Mark, A. G., Lee, T., Son, K., Chen, W., Alarcon-Correa, M., Kim, I., Schütz, G., Fischer, P. Selectable Nanopattern Arrays for Nanolithographic Imprint and Etch-Mask Applications Adv. Science, 2(7):1500016, 2015, Featured cover article. (article)

link (url) DOI [BibTex]