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2019


Life Improvement Science: A Manifesto
Life Improvement Science: A Manifesto

Lieder, F.

December 2019 (article) In revision

Abstract
Rapid technological advances present unprecedented opportunities for helping people thrive. This manifesto presents a road map for establishing a solid scientific foundation upon which those opportunities can be realized. It highlights fundamental open questions about the cognitive underpinnings of effective living and how they can be improved, supported, and augmented. These questions are at the core of my proposal for a new transdisciplinary research area called life improvement science. Recent advances have made these questions amenable to scientific rigor, and emerging approaches are paving the way towards practical strategies, clever interventions, and (intelligent) apps for empowering people to reach unprecedented levels of personal effectiveness and wellbeing.

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Life improvement science: a manifesto DOI [BibTex]


Decoding subcategories of human bodies from both body- and face-responsive cortical regions
Decoding subcategories of human bodies from both body- and face-responsive cortical regions

Foster, C., Zhao, M., Romero, J., Black, M. J., Mohler, B. J., Bartels, A., Bülthoff, I.

NeuroImage, 202(15):116085, November 2019 (article)

Abstract
Our visual system can easily categorize objects (e.g. faces vs. bodies) and further differentiate them into subcategories (e.g. male vs. female). This ability is particularly important for objects of social significance, such as human faces and bodies. While many studies have demonstrated category selectivity to faces and bodies in the brain, how subcategories of faces and bodies are represented remains unclear. Here, we investigated how the brain encodes two prominent subcategories shared by both faces and bodies, sex and weight, and whether neural responses to these subcategories rely on low-level visual, high-level visual or semantic similarity. We recorded brain activity with fMRI while participants viewed faces and bodies that varied in sex, weight, and image size. The results showed that the sex of bodies can be decoded from both body- and face-responsive brain areas, with the former exhibiting more consistent size-invariant decoding than the latter. Body weight could also be decoded in face-responsive areas and in distributed body-responsive areas, and this decoding was also invariant to image size. The weight of faces could be decoded from the fusiform body area (FBA), and weight could be decoded across face and body stimuli in the extrastriate body area (EBA) and a distributed body-responsive area. The sex of well-controlled faces (e.g. excluding hairstyles) could not be decoded from face- or body-responsive regions. These results demonstrate that both face- and body-responsive brain regions encode information that can distinguish the sex and weight of bodies. Moreover, the neural patterns corresponding to sex and weight were invariant to image size and could sometimes generalize across face and body stimuli, suggesting that such subcategorical information is encoded with a high-level visual or semantic code.

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paper pdf DOI [BibTex]

paper pdf DOI [BibTex]


Fast Feedback Control over Multi-hop Wireless Networks with Mode Changes and Stability Guarantees
Fast Feedback Control over Multi-hop Wireless Networks with Mode Changes and Stability Guarantees

Baumann, D., Mager, F., Jacob, R., Thiele, L., Zimmerling, M., Trimpe, S.

ACM Transactions on Cyber-Physical Systems, 4(2):18, November 2019 (article)

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arXiv PDF DOI [BibTex]

arXiv PDF DOI [BibTex]


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Doing More with Less: Meta-Reasoning and Meta-Learning in Humans and Machines

Griffiths, T. L., Callaway, F., Chang, M. B., Grant, E., Krueger, P. M., Lieder, F.

Current Opinion in Behavioral Sciences, 29, pages: 24-30, October 2019 (article)

Abstract
Artificial intelligence systems use an increasing amount of computation and data to solve very specific problems. By contrast, human minds solve a wide range of problems using a fixed amount of computation and limited experience. We identify two abilities that we see as crucial to this kind of general intelligence: meta-reasoning (deciding how to allocate computational resources) and meta-learning (modeling the learning environment to make better use of limited data). We summarize the relevant AI literature and relate the resulting ideas to recent work in psychology.

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DOI [BibTex]

DOI [BibTex]


Active Perception based Formation Control for Multiple Aerial Vehicles
Active Perception based Formation Control for Multiple Aerial Vehicles

Tallamraju, R., Price, E., Ludwig, R., Karlapalem, K., Bülthoff, H. H., Black, M. J., Ahmad, A.

IEEE Robotics and Automation Letters, Robotics and Automation Letters, 4(4):4491-4498, IEEE, October 2019 (article)

Abstract
We present a novel robotic front-end for autonomous aerial motion-capture (mocap) in outdoor environments. In previous work, we presented an approach for cooperative detection and tracking (CDT) of a subject using multiple micro-aerial vehicles (MAVs). However, it did not ensure optimal view-point configurations of the MAVs to minimize the uncertainty in the person's cooperatively tracked 3D position estimate. In this article, we introduce an active approach for CDT. In contrast to cooperatively tracking only the 3D positions of the person, the MAVs can actively compute optimal local motion plans, resulting in optimal view-point configurations, which minimize the uncertainty in the tracked estimate. We achieve this by decoupling the goal of active tracking into a quadratic objective and non-convex constraints corresponding to angular configurations of the MAVs w.r.t. the person. We derive this decoupling using Gaussian observation model assumptions within the CDT algorithm. We preserve convexity in optimization by embedding all the non-convex constraints, including those for dynamic obstacle avoidance, as external control inputs in the MPC dynamics. Multiple real robot experiments and comparisons involving 3 MAVs in several challenging scenarios are presented.

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pdf DOI Project Page [BibTex]

pdf DOI Project Page [BibTex]


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Decoding the Viewpoint and Identity of Faces and Bodies

Foster, C., Zhao, M., Bolkart, T., Black, M., Bartels, A., Bülthoff, I.

Journal of Vision, 19(10): 54c, pages: 54-55, Arvo Journals, September 2019 (article)

Abstract
(2019). . , 19(10): 25.13, 54-55. doi: Zitierlink: http://hdl.handle.net/21.11116/0000-0003-7493-4

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


Cognitive Prostheses for Goal Achievement
Cognitive Prostheses for Goal Achievement

Lieder, F., Chen, O. X., Krueger, P. M., Griffiths, T. L.

Nature Human Behavior, 3, August 2019 (article)

Abstract
Procrastination and impulsivity take a significant toll on people’s lives and the economy at large. Both can result from the misalignment of an action's proximal rewards with its long-term value. Therefore, aligning immediate reward with long-term value could be a way to help people overcome motivational barriers and make better decisions. Previous research has shown that game elements, such as points, levels, and badges, can be used to motivate people and nudge their decisions on serious matters. Here, we develop a new approach to decision support that leveragesartificial intelligence and game elements to restructure challenging sequential decision problems in such a way that it becomes easier for people to take the right course of action. A series of four increasingly more realistic experiments suggests that this approach can enable people to make better decisions faster, procrastinate less, complete their work on time, and waste less time on unimportant tasks. These findings suggest that our method is a promising step towards developing cognitive prostheses that help people achieve their goals by enhancing their motivation and decision-making in everyday life.

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DOI [BibTex]

DOI [BibTex]


Resource-aware IoT Control: Saving Communication through Predictive Triggering
Resource-aware IoT Control: Saving Communication through Predictive Triggering

Trimpe, S., Baumann, D.

IEEE Internet of Things Journal, 6(3):5013-5028, June 2019 (article)

Abstract
The Internet of Things (IoT) interconnects multiple physical devices in large-scale networks. When the 'things' coordinate decisions and act collectively on shared information, feedback is introduced between them. Multiple feedback loops are thus closed over a shared, general-purpose network. Traditional feedback control is unsuitable for design of IoT control because it relies on high-rate periodic communication and is ignorant of the shared network resource. Therefore, recent event-based estimation methods are applied herein for resource-aware IoT control allowing agents to decide online whether communication with other agents is needed, or not. While this can reduce network traffic significantly, a severe limitation of typical event-based approaches is the need for instantaneous triggering decisions that leave no time to reallocate freed resources (e.g., communication slots), which hence remain unused. To address this problem, novel predictive and self triggering protocols are proposed herein. From a unified Bayesian decision framework, two schemes are developed: self triggers that predict, at the current triggering instant, the next one; and predictive triggers that check at every time step, whether communication will be needed at a given prediction horizon. The suitability of these triggers for feedback control is demonstrated in hardware experiments on a cart-pole, and scalability is discussed with a multi-vehicle simulation.

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PDF arXiv DOI [BibTex]

PDF arXiv DOI [BibTex]


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Resource-rational analysis: Understanding human cognition as the optimal use of limited computational resources

Lieder, F., Griffiths, T. L.

Behavioral and Brain Sciences, 43, E1, Febuary 2019 (article)

Abstract
Modeling human cognition is challenging because there are infinitely many mechanisms that can generate any given observation. Some researchers address this by constraining the hypothesis space through assumptions about what the human mind can and cannot do, while others constrain it through principles of rationality and adaptation. Recent work in economics, psychology, neuroscience, and linguistics has begun to integrate both approaches by augmenting rational models with cognitive constraints, incorporating rational principles into cognitive architectures, and applying optimality principles to understanding neural representations. We identify the rational use of limited resources as a unifying principle underlying these diverse approaches, expressing it in a new cognitive modeling paradigm called resource-rational analysis. The integration of rational principles with realistic cognitive constraints makes resource-rational analysis a promising framework for reverse-engineering cognitive mechanisms and representations. It has already shed new light on the debate about human rationality and can be leveraged to revisit classic questions of cognitive psychology within a principled computational framework. We demonstrate that resource-rational models can reconcile the mind's most impressive cognitive skills with people's ostensive irrationality. Resource-rational analysis also provides a new way to connect psychological theory more deeply with artificial intelligence, economics, neuroscience, and linguistics.

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DOI [BibTex]

DOI [BibTex]


 Perceptual Effects of Inconsistency in Human Animations
Perceptual Effects of Inconsistency in Human Animations

Kenny, S., Mahmood, N., Honda, C., Black, M. J., Troje, N. F.

ACM Trans. Appl. Percept., 16(1):2:1-2:18, Febuary 2019 (article)

Abstract
The individual shape of the human body, including the geometry of its articulated structure and the distribution of weight over that structure, influences the kinematics of a person’s movements. How sensitive is the visual system to inconsistencies between shape and motion introduced by retargeting motion from one person onto the shape of another? We used optical motion capture to record five pairs of male performers with large differences in body weight, while they pushed, lifted, and threw objects. From these data, we estimated both the kinematics of the actions as well as the performer’s individual body shape. To obtain consistent and inconsistent stimuli, we created animated avatars by combining the shape and motion estimates from either a single performer or from different performers. Using these stimuli we conducted three experiments in an immersive virtual reality environment. First, a group of participants detected which of two stimuli was inconsistent. Performance was very low, and results were only marginally significant. Next, a second group of participants rated perceived attractiveness, eeriness, and humanness of consistent and inconsistent stimuli, but these judgements of animation characteristics were not affected by consistency of the stimuli. Finally, a third group of participants rated properties of the objects rather than of the performers. Here, we found strong influences of shape-motion inconsistency on perceived weight and thrown distance of objects. This suggests that the visual system relies on its knowledge of shape and motion and that these components are assimilated into an altered perception of the action outcome. We propose that the visual system attempts to resist inconsistent interpretations of human animations. Actions involving object manipulations present an opportunity for the visual system to reinterpret the introduced inconsistencies as a change in the dynamics of an object rather than as an unexpected combination of body shape and body motion.

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publisher pdf DOI [BibTex]

publisher pdf DOI [BibTex]


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Co-Contraction facilitates Body Stiffness Modulation during Swimming with Sensory Feedback in a Soft Biorobotic Physical Model

Jusufi, A., Vogt, D., Wood, R. J.

Integrative and Comparative Biology, 59(Supplement 1):E116-E116, Society of Integrative and Comparative Biology, McLean, VA, 2019 (article)

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DOI [BibTex]

DOI [BibTex]


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Self and Body Part Localization in Virtual Reality: Comparing a Headset and a Large-Screen Immersive Display

van der Veer, A. H., Longo, M. R., Alsmith, A. J. T., Wong, H. Y., Mohler, B. J.

Frontiers in Robotics and AI, 6(33), 2019 (article)

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DOI [BibTex]

DOI [BibTex]


The Virtual Caliper: Rapid Creation of Metrically Accurate Avatars from {3D} Measurements
The Virtual Caliper: Rapid Creation of Metrically Accurate Avatars from 3D Measurements

Pujades, S., Mohler, B., Thaler, A., Tesch, J., Mahmood, N., Hesse, N., Bülthoff, H. H., Black, M. J.

IEEE Transactions on Visualization and Computer Graphics, 25(5):1887-1897, IEEE, 2019 (article)

Abstract
Creating metrically accurate avatars is important for many applications such as virtual clothing try-on, ergonomics, medicine, immersive social media, telepresence, and gaming. Creating avatars that precisely represent a particular individual is challenging however, due to the need for expensive 3D scanners, privacy issues with photographs or videos, and difficulty in making accurate tailoring measurements. We overcome these challenges by creating “The Virtual Caliper”, which uses VR game controllers to make simple measurements. First, we establish what body measurements users can reliably make on their own body. We find several distance measurements to be good candidates and then verify that these are linearly related to 3D body shape as represented by the SMPL body model. The Virtual Caliper enables novice users to accurately measure themselves and create an avatar with their own body shape. We evaluate the metric accuracy relative to ground truth 3D body scan data, compare the method quantitatively to other avatar creation tools, and perform extensive perceptual studies. We also provide a software application to the community that enables novices to rapidly create avatars in fewer than five minutes. Not only is our approach more rapid than existing methods, it exports a metrically accurate 3D avatar model that is rigged and skinned.

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Project Page IEEE Open Access IEEE Open Access PDF DOI [BibTex]

Project Page IEEE Open Access IEEE Open Access PDF DOI [BibTex]


A Rational Reinterpretation of Dual Process Theories
A Rational Reinterpretation of Dual Process Theories

Milli, S., Lieder, F., Griffiths, T. L.

2019 (article)

Abstract
Highly influential "dual-process" accounts of human cognition postulate the coexistence of a slow accurate system with a fast error-prone system. But why would there be just two systems rather than, say, one or 93? Here, we argue that a dual-process architecture might be neither arbitrary nor irrational, but might instead reflect a rational tradeoff between the cognitive flexibility afforded by multiple systems and the time and effort required to choose between them. We investigate what the optimal set and number of cognitive systems would be depending on the structure of the environment. We find that the optimal number of systems depends on the variability of the environment and the difficulty of deciding when which system should be used. Furthermore, when having two systems is optimal, then the first system is fast but error-prone and the second system is slow but accurate. Our findings thereby provide a rational reinterpretation of dual-process theories.

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DOI [BibTex]

DOI [BibTex]

2014


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Wenn es was zu sagen gibt

(Klaus Tschira Award 2014 in Computer Science)

Trimpe, S.

Bild der Wissenschaft, pages: 20-23, November 2014, (popular science article in German) (article)

am ics

PDF Project Page [BibTex]

2014


PDF Project Page [BibTex]


{MoSh}: Motion and Shape Capture from Sparse Markers
MoSh: Motion and Shape Capture from Sparse Markers

Loper, M. M., Mahmood, N., Black, M. J.

ACM Transactions on Graphics, (Proc. SIGGRAPH Asia), 33(6):220:1-220:13, ACM, New York, NY, USA, November 2014 (article)

Abstract
Marker-based motion capture (mocap) is widely criticized as producing lifeless animations. We argue that important information about body surface motion is present in standard marker sets but is lost in extracting a skeleton. We demonstrate a new approach called MoSh (Motion and Shape capture), that automatically extracts this detail from mocap data. MoSh estimates body shape and pose together using sparse marker data by exploiting a parametric model of the human body. In contrast to previous work, MoSh solves for the marker locations relative to the body and estimates accurate body shape directly from the markers without the use of 3D scans; this effectively turns a mocap system into an approximate body scanner. MoSh is able to capture soft tissue motions directly from markers by allowing body shape to vary over time. We evaluate the effect of different marker sets on pose and shape accuracy and propose a new sparse marker set for capturing soft-tissue motion. We illustrate MoSh by recovering body shape, pose, and soft-tissue motion from archival mocap data and using this to produce animations with subtlety and realism. We also show soft-tissue motion retargeting to new characters and show how to magnify the 3D deformations of soft tissue to create animations with appealing exaggerations.

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pdf video data pdf from publisher link (url) DOI Project Page Project Page Project Page [BibTex]

pdf video data pdf from publisher link (url) DOI Project Page Project Page Project Page [BibTex]


Can I recognize my body’s weight? The influence of shape and texture on the perception of self
Can I recognize my body’s weight? The influence of shape and texture on the perception of self

Piryankova, I., Stefanucci, J., Romero, J., de la Rosa, S., Black, M., Mohler, B.

ACM Transactions on Applied Perception for the Symposium on Applied Perception, 11(3):13:1-13:18, September 2014 (article)

Abstract
The goal of this research was to investigate women’s sensitivity to changes in their perceived weight by altering the body mass index (BMI) of the participants’ personalized avatars displayed on a large-screen immersive display. We created the personalized avatars with a full-body 3D scanner that records both the participants’ body geometry and texture. We altered the weight of the personalized avatars to produce changes in BMI while keeping height, arm length and inseam fixed and exploited the correlation between body geometry and anthropometric measurements encapsulated in a statistical body shape model created from thousands of body scans. In a 2x2 psychophysical experiment, we investigated the relative importance of visual cues, namely shape (own shape vs. an average female body shape with equivalent height and BMI to the participant) and texture (own photo-realistic texture or checkerboard pattern texture) on the ability to accurately perceive own current body weight (by asking them ‘Is the avatar the same weight as you?’). Our results indicate that shape (where height and BMI are fixed) had little effect on the perception of body weight. Interestingly, the participants perceived their body weight veridically when they saw their own photo-realistic texture and significantly underestimated their body weight when the avatar had a checkerboard patterned texture. The range that the participants accepted as their own current weight was approximately a 0.83 to −6.05 BMI% change tolerance range around their perceived weight. Both the shape and the texture had an effect on the reported similarity of the body parts and the whole avatar to the participant’s body. This work has implications for new measures for patients with body image disorders, as well as researchers interested in creating personalized avatars for games, training applications or virtual reality.

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pdf DOI Project Page Project Page [BibTex]

pdf DOI Project Page Project Page [BibTex]


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3D to 2D bijection for spherical objects under equidistant fisheye projection

Ahmad, A., Xavier, J., Santos-Victor, J., Lima, P.

Computer Vision and Image Understanding, 125, pages: 172-183, August 2014 (article)

Abstract
The core problem addressed in this article is the 3D position detection of a spherical object of known-radius in a single image frame, obtained by a dioptric vision system consisting of only one fisheye lens camera that follows equidistant projection model. The central contribution is a bijection principle between a known-radius spherical object’s 3D world position and its 2D projected image curve, that we prove, thus establishing that for every possible 3D world position of the spherical object, there exists a unique curve on the image plane if the object is projected through a fisheye lens that follows equidistant projection model. Additionally, we present a setup for the experimental verification of the principle’s correctness. In previously published works we have applied this principle to detect and subsequently track a known-radius spherical object.

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DOI [BibTex]

DOI [BibTex]


Breathing Life into Shape: Capturing, Modeling and Animating {3D} Human Breathing
Breathing Life into Shape: Capturing, Modeling and Animating 3D Human Breathing

Tsoli, A., Mahmood, N., Black, M. J.

ACM Transactions on Graphics, (Proc. SIGGRAPH), 33(4):52:1-52:11, ACM, New York, NY, July 2014 (article)

Abstract
Modeling how the human body deforms during breathing is important for the realistic animation of lifelike 3D avatars. We learn a model of body shape deformations due to breathing for different breathing types and provide simple animation controls to render lifelike breathing regardless of body shape. We capture and align high-resolution 3D scans of 58 human subjects. We compute deviations from each subject’s mean shape during breathing, and study the statistics of such shape changes for different genders, body shapes, and breathing types. We use the volume of the registered scans as a proxy for lung volume and learn a novel non-linear model relating volume and breathing type to 3D shape deformations and pose changes. We then augment a SCAPE body model so that body shape is determined by identity, pose, and the parameters of the breathing model. These parameters provide an intuitive interface with which animators can synthesize 3D human avatars with realistic breathing motions. We also develop a novel interface for animating breathing using a spirometer, which measures the changes in breathing volume of a “breath actor.”

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pdf video link (url) DOI Project Page Project Page Project Page [BibTex]


3D Traffic Scene Understanding from Movable Platforms
3D Traffic Scene Understanding from Movable Platforms

Geiger, A., Lauer, M., Wojek, C., Stiller, C., Urtasun, R.

IEEE Transactions on Pattern Analysis and Machine Intelligence (PAMI), 36(5):1012-1025, published, IEEE, Los Alamitos, CA, May 2014 (article)

Abstract
In this paper, we present a novel probabilistic generative model for multi-object traffic scene understanding from movable platforms which reasons jointly about the 3D scene layout as well as the location and orientation of objects in the scene. In particular, the scene topology, geometry and traffic activities are inferred from short video sequences. Inspired by the impressive driving capabilities of humans, our model does not rely on GPS, lidar or map knowledge. Instead, it takes advantage of a diverse set of visual cues in the form of vehicle tracklets, vanishing points, semantic scene labels, scene flow and occupancy grids. For each of these cues we propose likelihood functions that are integrated into a probabilistic generative model. We learn all model parameters from training data using contrastive divergence. Experiments conducted on videos of 113 representative intersections show that our approach successfully infers the correct layout in a variety of very challenging scenarios. To evaluate the importance of each feature cue, experiments using different feature combinations are conducted. Furthermore, we show how by employing context derived from the proposed method we are able to improve over the state-of-the-art in terms of object detection and object orientation estimation in challenging and cluttered urban environments.

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pdf link (url) [BibTex]

pdf link (url) [BibTex]


Adaptive Offset Correction for Intracortical Brain Computer Interfaces
Adaptive Offset Correction for Intracortical Brain Computer Interfaces

Homer, M. L., Perge, J. A., Black, M. J., Harrison, M. T., Cash, S. S., Hochberg, L. R.

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 22(2):239-248, March 2014 (article)

Abstract
Intracortical brain computer interfaces (iBCIs) decode intended movement from neural activity for the control of external devices such as a robotic arm. Standard approaches include a calibration phase to estimate decoding parameters. During iBCI operation, the statistical properties of the neural activity can depart from those observed during calibration, sometimes hindering a user’s ability to control the iBCI. To address this problem, we adaptively correct the offset terms within a Kalman filter decoder via penalized maximum likelihood estimation. The approach can handle rapid shifts in neural signal behavior (on the order of seconds) and requires no knowledge of the intended movement. The algorithm, called MOCA, was tested using simulated neural activity and evaluated retrospectively using data collected from two people with tetraplegia operating an iBCI. In 19 clinical research test cases, where a nonadaptive Kalman filter yielded relatively high decoding errors, MOCA significantly reduced these errors (10.6 ± 10.1\%; p < 0.05, pairwise t-test). MOCA did not significantly change the error in the remaining 23 cases where a nonadaptive Kalman filter already performed well. These results suggest that MOCA provides more robust decoding than the standard Kalman filter for iBCIs.

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pdf DOI Project Page [BibTex]

pdf DOI Project Page [BibTex]


A physically-based approach to reflection separation: from physical modeling to constrained optimization
A physically-based approach to reflection separation: from physical modeling to constrained optimization

Kong, N., Tai, Y., Shin, J. S.

IEEE Transactions on Pattern Analysis and Machine Intelligence (PAMI), 36(2):209-221, IEEE Computer Society, Febuary 2014 (article)

Abstract
We propose a physically-based approach to separate reflection using multiple polarized images with a background scene captured behind glass. The input consists of three polarized images, each captured from the same view point but with a different polarizer angle separated by 45 degrees. The output is the high-quality separation of the reflection and background layers from each of the input images. A main technical challenge for this problem is that the mixing coefficient for the reflection and background layers depends on the angle of incidence and the orientation of the plane of incidence, which are spatially varying over the pixels of an image. Exploiting physical properties of polarization for a double-surfaced glass medium, we propose a multiscale scheme which automatically finds the optimal separation of the reflection and background layers. Through experiments, we demonstrate that our approach can generate superior results to those of previous methods.

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Publisher site [BibTex]

Publisher site [BibTex]


Simpler, faster, more accurate melanocytic lesion segmentation through MEDS
Simpler, faster, more accurate melanocytic lesion segmentation through MEDS

Peruch, F., Bogo, F., Bonazza, M., Cappelleri, V., Peserico, E.

IEEE Transactions on Biomedical Engineering, 61(2):557-565, February 2014 (article)

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DOI [BibTex]

DOI [BibTex]


Learning People Detectors for Tracking in Crowded Scenes.
Learning People Detectors for Tracking in Crowded Scenes.

Tang, S., Andriluka, M., Milan, A., Schindler, K., Roth, S., Schiele, B.

2014, Scene Understanding Workshop (SUNw, CVPR workshop) (unpublished)

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[BibTex]

[BibTex]


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A Limiting Property of the Matrix Exponential

Trimpe, S., D’Andrea, R.

IEEE Transactions on Automatic Control, 59(4):1105-1110, 2014 (article)

am ics

PDF DOI [BibTex]

PDF DOI [BibTex]


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Event-Based State Estimation With Variance-Based Triggering

Trimpe, S., D’Andrea, R.

IEEE Transactions on Automatic Control, 59(12):3266-3281, 2014 (article)

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PDF Supplementary material DOI Project Page [BibTex]

PDF Supplementary material DOI Project Page [BibTex]


A freely-moving monkey treadmill model
A freely-moving monkey treadmill model

Foster, J., Nuyujukian, P., Freifeld, O., Gao, H., Walker, R., Ryu, S., Meng, T., Murmann, B., Black, M., Shenoy, K.

J. of Neural Engineering, 11(4):046020, 2014 (article)

Abstract
Objective: Motor neuroscience and brain-machine interface (BMI) design is based on examining how the brain controls voluntary movement, typically by recording neural activity and behavior from animal models. Recording technologies used with these animal models have traditionally limited the range of behaviors that can be studied, and thus the generality of science and engineering research. We aim to design a freely-moving animal model using neural and behavioral recording technologies that do not constrain movement. Approach: We have established a freely-moving rhesus monkey model employing technology that transmits neural activity from an intracortical array using a head-mounted device and records behavior through computer vision using markerless motion capture. We demonstrate the excitability and utility of this new monkey model, including the fi rst recordings from motor cortex while rhesus monkeys walk quadrupedally on a treadmill. Main results: Using this monkey model, we show that multi-unit threshold-crossing neural activity encodes the phase of walking and that the average ring rate of the threshold crossings covaries with the speed of individual steps. On a population level, we find that neural state-space trajectories of walking at diff erent speeds have similar rotational dynamics in some dimensions that evolve at the step rate of walking, yet robustly separate by speed in other state-space dimensions. Significance: Freely-moving animal models may allow neuroscientists to examine a wider range of behaviors and can provide a flexible experimental paradigm for examining the neural mechanisms that underlie movement generation across behaviors and environments. For BMIs, freely-moving animal models have the potential to aid prosthetic design by examining how neural encoding changes with posture, environment, and other real-world context changes. Understanding this new realm of behavior in more naturalistic settings is essential for overall progress of basic motor neuroscience and for the successful translation of BMIs to people with paralysis.

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pdf Supplementary DOI Project Page [BibTex]

pdf Supplementary DOI Project Page [BibTex]


A Quantitative Analysis of Current Practices in Optical Flow Estimation and the Principles behind Them
A Quantitative Analysis of Current Practices in Optical Flow Estimation and the Principles behind Them

(Journal version of the Longuet-Higgins Prize paper on "Secrets of Optical Flow")

Sun, D., Roth, S., Black, M. J.

International Journal of Computer Vision (IJCV), 106(2):115-137, 2014 (article)

Abstract
The accuracy of optical flow estimation algorithms has been improving steadily as evidenced by results on the Middlebury optical flow benchmark. The typical formulation, however, has changed little since the work of Horn and Schunck. We attempt to uncover what has made recent advances possible through a thorough analysis of how the objective function, the optimization method, and modern implementation practices influence accuracy. We discover that "classical'' flow formulations perform surprisingly well when combined with modern optimization and implementation techniques. One key implementation detail is the median filtering of intermediate flow fields during optimization. While this improves the robustness of classical methods it actually leads to higher energy solutions, meaning that these methods are not optimizing the original objective function. To understand the principles behind this phenomenon, we derive a new objective function that formalizes the median filtering heuristic. This objective function includes a non-local smoothness term that robustly integrates flow estimates over large spatial neighborhoods. By modifying this new term to include information about flow and image boundaries we develop a method that can better preserve motion details. To take advantage of the trend towards video in wide-screen format, we further introduce an asymmetric pyramid downsampling scheme that enables the estimation of longer range horizontal motions. The methods are evaluated on Middlebury, MPI Sintel, and KITTI datasets using the same parameter settings.

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pdf full text code [BibTex]

pdf full text code [BibTex]


Detection and Tracking of Occluded People
Detection and Tracking of Occluded People

Tang, S., Andriluka, M., Schiele, B.

International Journal of Computer Vision, 110, pages: 58-69, 2014 (article)

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PDF [BibTex]

PDF [BibTex]


Segmentation of Biomedical Images Using Active Contour Model with Robust Image Feature and Shape Prior
Segmentation of Biomedical Images Using Active Contour Model with Robust Image Feature and Shape Prior

S. Y. Yeo, X. Xie, I. Sazonov, P. Nithiarasu

International Journal for Numerical Methods in Biomedical Engineering, 30(2):232- 248, 2014 (article)

Abstract
In this article, a new level set model is proposed for the segmentation of biomedical images. The image energy of the proposed model is derived from a robust image gradient feature which gives the active contour a global representation of the geometric configuration, making it more robust in dealing with image noise, weak edges, and initial configurations. Statistical shape information is incorporated using nonparametric shape density distribution, which allows the shape model to handle relatively large shape variations. The segmentation of various shapes from both synthetic and real images depict the robustness and efficiency of the proposed method.

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[BibTex]

[BibTex]


Automatic 4D Reconstruction of Patient-Specific Cardiac Mesh with 1- to-1 Vertex Correspondence from Segmented Contours Lines
Automatic 4D Reconstruction of Patient-Specific Cardiac Mesh with 1- to-1 Vertex Correspondence from Segmented Contours Lines

C. W. Lim, Y. Su, S. Y. Yeo, G. M. Ng, V. T. Nguyen, L. Zhong, R. S. Tan, K. K. Poh, P. Chai,

PLOS ONE, 9(4), 2014 (article)

Abstract
We propose an automatic algorithm for the reconstruction of patient-specific cardiac mesh models with 1-to-1 vertex correspondence. In this framework, a series of 3D meshes depicting the endocardial surface of the heart at each time step is constructed, based on a set of border delineated magnetic resonance imaging (MRI) data of the whole cardiac cycle. The key contribution in this work involves a novel reconstruction technique to generate a 4D (i.e., spatial–temporal) model of the heart with 1-to-1 vertex mapping throughout the time frames. The reconstructed 3D model from the first time step is used as a base template model and then deformed to fit the segmented contours from the subsequent time steps. A method to determine a tree-based connectivity relationship is proposed to ensure robust mapping during mesh deformation. The novel feature is the ability to handle intra- and inter-frame 2D topology changes of the contours, which manifests as a series of merging and splitting of contours when the images are viewed either in a spatial or temporal sequence. Our algorithm has been tested on five acquisitions of cardiac MRI and can successfully reconstruct the full 4D heart model in around 30 minutes per subject. The generated 4D heart model conforms very well with the input segmented contours and the mesh element shape is of reasonably good quality. The work is important in the support of downstream computational simulation activities.

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[BibTex]

[BibTex]

2011


High-quality reflection separation using polarized images
High-quality reflection separation using polarized images

Kong, N., Tai, Y., Shin, S. Y.

IEEE Transactions on Image Processing, 20(12):3393-3405, IEEE Signal Processing Society, December 2011 (article)

Abstract
In this paper, we deal with a problem of separating the effect of reflection from images captured behind glass. The input consists of multiple polarized images captured from the same view point but with different polarizer angles. The output is the high quality separation of the reflection layer and the background layer from the images. We formulate this problem as a constrained optimization problem and propose a framework that allows us to fully exploit the mutually exclusive image information in our input data. We test our approach on various images and demonstrate that our approach can generate good reflection separation results.

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Publisher site [BibTex]

2011


Publisher site [BibTex]


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A human inspired gaze estimation system

Wulff, J., Sinha, P.

Journal of Vision, 11(11):507-507, ARVO, September 2011 (article)

Abstract
Estimating another person's gaze is a crucial skill in human social interactions. The social component is most apparent in dyadic gaze situations, in which the looker seems to look into the eyes of the observer, thereby signaling interest or a turn to speak. In a triadic situation, on the other hand, the looker's gaze is averted from the observer and directed towards another, specific target. This is mostly interpreted as a cue for joint attention, creating awareness of a predator or another point of interest. In keeping with the task's social significance, humans are very proficient at gaze estimation. Our accuracy ranges from less than one degree for dyadic settings to approximately 2.5 degrees for triadic ones. Our goal in this work is to draw inspiration from human gaze estimation mechanisms in order to create an artificial system that can approach the former's accuracy levels. Since human performance is severely impaired by both image-based degradations (Ando, 2004) and a change of facial configurations (Jenkins & Langton, 2003), the underlying principles are believed to be based both on simple image cues such as contrast/brightness distribution and on more complex geometric processing to reconstruct the actual shape of the head. By incorporating both kinds of cues in our system's design, we are able to surpass the accuracy of existing eye-tracking systems, which rely exclusively on either image-based or geometry-based cues (Yamazoe et al., 2008). A side-benefit of this combined approach is that it allows for gaze estimation despite moderate view-point changes. This is important for settings where subjects, say young children or certain kinds of patients, might not be fully cooperative to allow a careful calibration. Our model and implementation of gaze estimation opens up new experimental questions about human mechanisms while also providing a useful tool for general calibration-free, non-intrusive remote eye-tracking.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


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Detecting synchrony in degraded audio-visual streams

Dhandhania, K., Wulff, J., Sinha, P.

Journal of Vision, 11(11):800-800, ARVO, September 2011 (article)

Abstract
Even 8–10 week old infants, when presented with two dynamic faces and a speech stream, look significantly longer at the ‘correct’ talking person (Patterson & Werker, 2003). This is true even though their reduced visual acuity prevents them from utilizing high spatial frequencies. Computational analyses in the field of audio/video synchrony and automatic speaker detection (e.g. Hershey & Movellan, 2000), in contrast, usually depend on high-resolution images. Therefore, the correlation mechanisms found in these computational studies are not directly applicable to the processes through which we learn to integrate the modalities of speech and vision. In this work, we investigated the correlation between speech signals and degraded video signals. We found a high correlation persisting even with high image degradation, resembling the low visual acuity of young infants. Additionally (in a fashion similar to Graf et al., 2002) we explored which parts of the face correlate with the audio in the degraded video sequences. Perfect synchrony and small offsets in the audio were used while finding the correlation, thereby detecting visual events preceding and following audio events. In order to achieve a sufficiently high temporal resolution, high-speed video sequences (500 frames per second) of talking people were used. This is a temporal resolution unachieved in previous studies and has allowed us to capture very subtle and short visual events. We believe that the results of this study might be interesting not only to vision researchers, but, by revealing subtle effects on a very fine timescale, also to people working in computer graphics and the generation and animation of artificial faces.

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link (url) DOI [BibTex]

link (url) DOI [BibTex]


Trajectory Space: A Dual Representation for Nonrigid Structure from Motion
Trajectory Space: A Dual Representation for Nonrigid Structure from Motion

Akhter, I., Sheikh, Y., Khan, S., Kanade, T.

Pattern Analysis and Machine Intelligence, IEEE Transactions on, 33(7):1442-1456, IEEE, July 2011 (article)

Abstract
Existing approaches to nonrigid structure from motion assume that the instantaneous 3D shape of a deforming object is a linear combination of basis shapes. These basis are object dependent and therefore have to be estimated anew for each video sequence. In contrast, we propose a dual approach to describe the evolving 3D structure in trajectory space by a linear combination of basis trajectories. We describe the dual relationship between the two approaches, showing that they both have equal power for representing 3D structure. We further show that the temporal smoothness in 3D trajectories alone can be used for recovering nonrigid structure from a moving camera. The principal advantage of expressing deforming 3D structure in trajectory space is that we can define an object independent basis. This results in a significant reduction in unknowns, and corresponding stability in estimation. We propose the use of the Discrete Cosine Transform (DCT) as the object independent basis and empirically demonstrate that it approaches Principal Component Analysis (PCA) for natural motions. We report the performance of the proposed method, quantitatively using motion capture data, and qualitatively on several video sequences exhibiting nonrigid motions including piecewise rigid motion, partially nonrigid motion (such as a facial expressions), and highly nonrigid motion (such as a person walking or dancing).

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pdf project page [BibTex]

pdf project page [BibTex]


Loose-limbed People: Estimating {3D} Human Pose and Motion Using Non-parametric Belief Propagation
Loose-limbed People: Estimating 3D Human Pose and Motion Using Non-parametric Belief Propagation

Sigal, L., Isard, M., Haussecker, H., Black, M. J.

International Journal of Computer Vision, 98(1):15-48, Springer Netherlands, May 2011 (article)

Abstract
We formulate the problem of 3D human pose estimation and tracking as one of inference in a graphical model. Unlike traditional kinematic tree representations, our model of the body is a collection of loosely-connected body-parts. In particular, we model the body using an undirected graphical model in which nodes correspond to parts and edges to kinematic, penetration, and temporal constraints imposed by the joints and the world. These constraints are encoded using pair-wise statistical distributions, that are learned from motion-capture training data. Human pose and motion estimation is formulated as inference in this graphical model and is solved using Particle Message Passing (PaMPas). PaMPas is a form of non-parametric belief propagation that uses a variation of particle filtering that can be applied over a general graphical model with loops. The loose-limbed model and decentralized graph structure allow us to incorporate information from "bottom-up" visual cues, such as limb and head detectors, into the inference process. These detectors enable automatic initialization and aid recovery from transient tracking failures. We illustrate the method by automatically tracking people in multi-view imagery using a set of calibrated cameras and present quantitative evaluation using the HumanEva dataset.

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pdf publisher's site link (url) Project Page Project Page [BibTex]

pdf publisher's site link (url) Project Page Project Page [BibTex]


Point-and-Click Cursor Control With an Intracortical Neural Interface System by Humans With Tetraplegia
Point-and-Click Cursor Control With an Intracortical Neural Interface System by Humans With Tetraplegia

Kim, S., Simeral, J. D., Hochberg, L. R., Donoghue, J. P., Friehs, G. M., Black, M. J.

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 19(2):193-203, April 2011 (article)

Abstract
We present a point-and-click intracortical neural interface system (NIS) that enables humans with tetraplegia to volitionally move a 2D computer cursor in any desired direction on a computer screen, hold it still and click on the area of interest. This direct brain-computer interface extracts both discrete (click) and continuous (cursor velocity) signals from a single small population of neurons in human motor cortex. A key component of this system is a multi-state probabilistic decoding algorithm that simultaneously decodes neural spiking activity and outputs either a click signal or the velocity of the cursor. The algorithm combines a linear classifier, which determines whether the user is intending to click or move the cursor, with a Kalman filter that translates the neural population activity into cursor velocity. We present a paradigm for training the multi-state decoding algorithm using neural activity observed during imagined actions. Two human participants with tetraplegia (paralysis of the four limbs) performed a closed-loop radial target acquisition task using the point-and-click NIS over multiple sessions. We quantified point-and-click performance using various human-computer interaction measurements for pointing devices. We found that participants were able to control the cursor motion accurately and click on specified targets with a small error rate (< 3% in one participant). This study suggests that signals from a small ensemble of motor cortical neurons (~40) can be used for natural point-and-click 2D cursor control of a personal computer.

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pdf publishers's site pub med link (url) Project Page [BibTex]

pdf publishers's site pub med link (url) Project Page [BibTex]


A Database and Evaluation Methodology for Optical Flow
A Database and Evaluation Methodology for Optical Flow

Baker, S., Scharstein, D., Lewis, J. P., Roth, S., Black, M. J., Szeliski, R.

International Journal of Computer Vision, 92(1):1-31, March 2011 (article)

Abstract
The quantitative evaluation of optical flow algorithms by Barron et al. (1994) led to significant advances in performance. The challenges for optical flow algorithms today go beyond the datasets and evaluation methods proposed in that paper. Instead, they center on problems associated with complex natural scenes, including nonrigid motion, real sensor noise, and motion discontinuities. We propose a new set of benchmarks and evaluation methods for the next generation of optical flow algorithms. To that end, we contribute four types of data to test different aspects of optical flow algorithms: (1) sequences with nonrigid motion where the ground-truth flow is determined by tracking hidden fluorescent texture, (2) realistic synthetic sequences, (3) high frame-rate video used to study interpolation error, and (4) modified stereo sequences of static scenes. In addition to the average angular error used by Barron et al., we compute the absolute flow endpoint error, measures for frame interpolation error, improved statistics, and results at motion discontinuities and in textureless regions. In October 2007, we published the performance of several well-known methods on a preliminary version of our data to establish the current state of the art. We also made the data freely available on the web at http://vision.middlebury.edu/flow/ . Subsequently a number of researchers have uploaded their results to our website and published papers using the data. A significant improvement in performance has already been achieved. In this paper we analyze the results obtained to date and draw a large number of conclusions from them.

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pdf pdf from publisher Middlebury Flow Evaluation Website [BibTex]

pdf pdf from publisher Middlebury Flow Evaluation Website [BibTex]


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Aerial righting reflexes in flightless animals

Jusufi, A., Zeng, Y., Full, R., Dudley, R.

Integ. Comp. Biol. , 2011 (article)

bio

[BibTex]

[BibTex]


Neural control of cursor trajectory and click by a human with tetraplegia 1000 days after implant of an intracortical microelectrode array
Neural control of cursor trajectory and click by a human with tetraplegia 1000 days after implant of an intracortical microelectrode array

(J. Neural Engineering Highlights of 2011 Collection. JNE top 10 cited papers of 2010-2011.)

Simeral, J. D., Kim, S., Black, M. J., Donoghue, J. P., Hochberg, L. R.

J. of Neural Engineering, 8(2):025027, 2011 (article)

Abstract
The ongoing pilot clinical trial of the BrainGate neural interface system aims in part to assess the feasibility of using neural activity obtained from a small-scale, chronically implanted, intracortical microelectrode array to provide control signals for a neural prosthesis system. Critical questions include how long implanted microelectrodes will record useful neural signals, how reliably those signals can be acquired and decoded, and how effectively they can be used to control various assistive technologies such as computers and robotic assistive devices, or to enable functional electrical stimulation of paralyzed muscles. Here we examined these questions by assessing neural cursor control and BrainGate system characteristics on five consecutive days 1000 days after implant of a 4 × 4 mm array of 100 microelectrodes in the motor cortex of a human with longstanding tetraplegia subsequent to a brainstem stroke. On each of five prospectively-selected days we performed time-amplitude sorting of neuronal spiking activity, trained a population-based Kalman velocity decoding filter combined with a linear discriminant click state classifier, and then assessed closed-loop point-and-click cursor control. The participant performed both an eight-target center-out task and a random target Fitts metric task which was adapted from a human-computer interaction ISO standard used to quantify performance of computer input devices. The neural interface system was further characterized by daily measurement of electrode impedances, unit waveforms and local field potentials. Across the five days, spiking signals were obtained from 41 of 96 electrodes and were successfully decoded to provide neural cursor point-and-click control with a mean task performance of 91.3% ± 0.1% (mean ± s.d.) correct target acquisition. Results across five consecutive days demonstrate that a neural interface system based on an intracortical microelectrode array can provide repeatable, accurate point-and-click control of a computer interface to an individual with tetraplegia 1000 days after implantation of this sensor.

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pdf pdf from publisher link (url) Project Page [BibTex]


Modelling pipeline for subject-specific arterial blood flow—A review
Modelling pipeline for subject-specific arterial blood flow—A review

Igor Sazonov, Si Yong Yeo, Rhodri Bevan, Xianghua Xie, Raoul van Loon, Perumal Nithiarasu

International Journal for Numerical Methods in Biomedical Engineering, 27(12):1868–1910, 2011 (article)

Abstract
In this paper, a robust and semi-automatic modelling pipeline for blood flow through subject-specific arterial geometries is presented. The framework developed consists of image segmentation, domain discretization (meshing) and fluid dynamics. All the three subtopics of the pipeline are explained using an example of flow through a severely stenosed human carotid artery. In the Introduction, the state-of-the-art of both image segmentation and meshing is presented in some detail, and wherever possible the advantages and disadvantages of the existing methods are analysed. Followed by this, the deformable model used for image segmentation is presented. This model is based upon a geometrical potential force (GPF), which is a function of the image. Both the GPF calculation and level set determination are explained. Following the image segmentation method, a semi-automatic meshing method used in the present study is explained in full detail. All the relevant techniques required to generate a valid domain discretization are presented. These techniques include generating a valid surface mesh, skeletonization, mesh cropping, boundary layer mesh construction and various mesh cosmetic methods that are essential for generating a high-quality domain discretization. After presenting the mesh generation procedure, how to generate flow boundary conditions for both the inlets and outlets of a geometry is explained in detail. This is followed by a brief note on the flow solver, before studying the blood flow through the carotid artery with a severe stenosis.

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[BibTex]

[BibTex]


 Geometrically Induced Force Interaction for Three-Dimensional Deformable Models
Geometrically Induced Force Interaction for Three-Dimensional Deformable Models

Si Yong Yeo, Xianghua Xie, Igor Sazonov, Perumal Nithiarasu

IEEE Transactions on Image Processing, 20(5):1373 - 1387, 2011 (article)

Abstract
In this paper, we propose a novel 3-D deformable model that is based upon a geometrically induced external force field which can be conveniently generalized to arbitrary dimensions. This external force field is based upon hypothesized interactions between the relative geometries of the deformable model and the object boundary characterized by image gradient. The evolution of the deformable model is solved using the level set method so that topological changes are handled automatically. The relative geometrical configurations between the deformable model and the object boundaries contribute to a dynamic vector force field that changes accordingly as the deformable model evolves. The geometrically induced dynamic interaction force has been shown to greatly improve the deformable model performance in acquiring complex geometries and highly concave boundaries, and it gives the deformable model a high invariancy in initialization configurations. The voxel interactions across the whole image domain provide a global view of the object boundary representation, giving the external force a long attraction range. The bidirectionality of the external force field allows the new deformable model to deal with arbitrary cross-boundary initializations, and facilitates the handling of weak edges and broken boundaries. In addition, we show that by enhancing the geometrical interaction field with a nonlocal edge-preserving algorithm, the new deformable model can effectively overcome image noise. We provide a comparative study on the segmentation of various geometries with different topologies from both synthetic and real images, and show that the proposed method achieves significant improvements against existing image gradient techniques.

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[BibTex]

[BibTex]


Predicting Articulated Human Motion from Spatial Processes
Predicting Articulated Human Motion from Spatial Processes

Soren Hauberg, Kim S. Pedersen

International Journal of Computer Vision, 94, pages: 317-334, Springer Netherlands, 2011 (article)

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Publishers site Code Paper site PDF [BibTex]

Publishers site Code Paper site PDF [BibTex]


Computational flow studies in a subject-specific human upper airway using a one-equation turbulence model. Influence of the nasal cavity
Computational flow studies in a subject-specific human upper airway using a one-equation turbulence model. Influence of the nasal cavity

Prihambodo Saksono, Perumal Nithiarasu, Igor Sazonov, Si Yong Yeo

International Journal for Numerical Methods in Biomedical Engineering, 87(1-5):96–114, 2011 (article)

Abstract
This paper focuses on the impact of including nasal cavity on airflow through a human upper respiratory tract. A computational study is carried out on a realistic geometry, reconstructed from CT scans of a subject. The geometry includes nasal cavity, pharynx, larynx, trachea and two generations of airway bifurcations below trachea. The unstructured mesh generation procedure is discussed in some length due to the complex nature of the nasal cavity structure and poor scan resolution normally available from hospitals. The fluid dynamic studies have been carried out on the geometry with and without the inclusion of the nasal cavity. The characteristic-based split scheme along with the one-equation Spalart–Allmaras turbulence model is used in its explicit form to obtain flow solutions at steady state. Results reveal that the exclusion of nasal cavity significantly influences the resulting solution. In particular, the location of recirculating flow in the trachea is dramatically different when the truncated geometry is used. In addition, we also address the differences in the solution due to imposed, equally distributed and proportionally distributed flow rates at inlets (both nares). The results show that the differences in flow pattern between the two inlet conditions are not confined to the nasal cavity and nasopharyngeal region, but they propagate down to the trachea.

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[BibTex]

[BibTex]

2008


A non-parametric {Bayesian} alternative to spike sorting
A non-parametric Bayesian alternative to spike sorting

Wood, F., Black, M. J.

J. Neuroscience Methods, 173(1):1–12, August 2008 (article)

Abstract
The analysis of extra-cellular neural recordings typically begins with careful spike sorting and all analysis of the data then rests on the correctness of the resulting spike trains. In many situations this is unproblematic as experimental and spike sorting procedures often focus on well isolated units. There is evidence in the literature, however, that errors in spike sorting can occur even with carefully collected and selected data. Additionally, chronically implanted electrodes and arrays with fixed electrodes cannot be easily adjusted to provide well isolated units. In these situations, multiple units may be recorded and the assignment of waveforms to units may be ambiguous. At the same time, analysis of such data may be both scientifically important and clinically relevant. In this paper we address this issue using a novel probabilistic model that accounts for several important sources of uncertainty and error in spike sorting. In lieu of sorting neural data to produce a single best spike train, we estimate a probabilistic model of spike trains given the observed data. We show how such a distribution over spike sortings can support standard neuroscientific questions while providing a representation of uncertainty in the analysis. As a representative illustration of the approach, we analyzed primary motor cortical tuning with respect to hand movement in data recorded with a chronic multi-electrode array in non-human primates.We found that the probabilistic analysis generally agrees with human sorters but suggests the presence of tuned units not detected by humans.

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pdf preprint pdf from publisher PubMed [BibTex]

2008


pdf preprint pdf from publisher PubMed [BibTex]


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Active tails enhance arboreal acrobatics in geckos

Jusufi, A., Goldman, D., Revzen, S., Full, R.

PNAS, 105(11):4215-4219, 2008 (article)

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link (url) [BibTex]

link (url) [BibTex]


Neural control of computer cursor velocity by decoding motor cortical spiking activity in humans with tetraplegia
Neural control of computer cursor velocity by decoding motor cortical spiking activity in humans with tetraplegia

(J. Neural Engineering Highlights of 2008 Collection)

Kim, S., Simeral, J., Hochberg, L., Donoghue, J. P., Black, M. J.

J. Neural Engineering, 5, pages: 455–476, 2008 (article)

Abstract
Computer-mediated connections between human motor cortical neurons and assistive devices promise to improve or restore lost function in people with paralysis. Recently, a pilot clinical study of an intracortical neural interface system demonstrated that a tetraplegic human was able to obtain continuous two-dimensional control of a computer cursor using neural activity recorded from his motor cortex. This control, however, was not sufficiently accurate for reliable use in many common computer control tasks. Here, we studied several central design choices for such a system including the kinematic representation for cursor movement, the decoding method that translates neuronal ensemble spiking activity into a control signal and the cursor control task used during training for optimizing the parameters of the decoding method. In two tetraplegic participants, we found that controlling a cursor’s velocity resulted in more accurate closed-loop control than controlling its position directly and that cursor velocity control was achieved more rapidly than position control. Control quality was further improved over conventional linear filters by using a probabilistic method, the Kalman filter, to decode human motor cortical activity. Performance assessment based on standard metrics used for the evaluation of a wide range of pointing devices demonstrated significantly improved cursor control with velocity rather than position decoding.

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pdf preprint pdf from publisher [BibTex]

pdf preprint pdf from publisher [BibTex]


Brownian Warps for Non-Rigid Registration
Brownian Warps for Non-Rigid Registration

Mads Nielsen, Peter Johansen, Andrew Jackson, Benny Lautrup, Soren Hauberg

Journal of Mathematical Imaging and Vision, 31, pages: 221-231, Springer Netherlands, 2008 (article)

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Publishers site PDF [BibTex]

Publishers site PDF [BibTex]


 An Efficient Algorithm for Modelling Duration in Hidden Markov Models, with a Dramatic Application
An Efficient Algorithm for Modelling Duration in Hidden Markov Models, with a Dramatic Application

Soren Hauberg, Jakob Sloth

Journal of Mathematical Imaging and Vision, 31, pages: 165-170, Springer Netherlands, 2008 (article)

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Publishers site Paper site PDF [BibTex]

Publishers site Paper site PDF [BibTex]