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2017


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Improving performance of linear field generation with multi-coil setup by optimizing coils position

Aghaeifar, A., Loktyushin, A., Eschelbach, M., Scheffler, K.

Magnetic Resonance Materials in Physics, Biology and Medicine, 30(Supplement 1):S259, 34th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB), October 2017 (poster)

ei

link (url) DOI [BibTex]

2017


link (url) DOI [BibTex]


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Editorial for the Special Issue on Microdevices and Microsystems for Cell Manipulation

Hu, W., Ohta, A. T.

8, Multidisciplinary Digital Publishing Institute, September 2017 (misc)

pi

DOI [BibTex]

DOI [BibTex]


Thumb xl full outfit
Physical and Behavioral Factors Improve Robot Hug Quality

Block, A. E., Kuchenbecker, K. J.

Workshop Paper (2 pages) presented at the RO-MAN Workshop on Social Interaction and Multimodal Expression for Socially Intelligent Robots, Lisbon, Portugal, August 2017 (misc)

Abstract
A hug is one of the most basic ways humans can express affection. As hugs are so common, a natural progression of robot development is to have robots one day hug humans as seamlessly as these intimate human-human interactions occur. This project’s purpose is to evaluate human responses to different robot physical characteristics and hugging behaviors. Specifically, we aim to test the hypothesis that a warm, soft, touch-sensitive PR2 humanoid robot can provide humans with satisfying hugs by matching both their hugging pressure and their hugging duration. Thirty participants experienced and evaluated twelve hugs with the robot, divided into three randomly ordered trials that focused on physical robot char- acteristics and nine randomly ordered trials with varied hug pressure and duration. We found that people prefer soft, warm hugs over hard, cold hugs. Furthermore, users prefer hugs that physically squeeze them and release immediately when they are ready for the hug to end.

hi

Project Page [BibTex]

Project Page [BibTex]


Thumb xl bodytalk
Crowdshaping Realistic 3D Avatars with Words

Streuber, S., Ramirez, M. Q., Black, M., Zuffi, S., O’Toole, A., Hill, M. Q., Hahn, C. A.

August 2017, Application PCT/EP2017/051954 (misc)

Abstract
A method for generating a body shape, comprising the steps: - receiving one or more linguistic descriptors related to the body shape; - retrieving an association between the one or more linguistic descriptors and a body shape; and - generating the body shape, based on the association.

ps

Google Patents [BibTex]

Google Patents [BibTex]


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Physically Interactive Exercise Games with a Baxter Robot

Fitter, N. T., Kuchenbecker, K. J.

Hands-on demonstration presented at the IEEE World Haptics Conference (WHC), Munich, Germany, June 2017 (misc)

hi

Project Page [BibTex]

Project Page [BibTex]


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Proton Pack: Visuo-Haptic Surface Data Recording

Burka, A., Kuchenbecker, K. J.

Hands-on demonstration presented at the IEEE World Haptics Conference (WHC), Munich, Germany, June 2017 (misc)

hi

Project Page [BibTex]

Project Page [BibTex]


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Teaching a Robot to Collaborate with a Human Via Haptic Teleoperation

Hu, S., Kuchenbecker, K. J.

Work-in-progress paper (2 pages) presented at the IEEE World Haptics Conference (WHC), Munich, Germany, June 2017 (misc)

hi

Project Page [BibTex]

Project Page [BibTex]


Thumb xl full outfit
How Should Robots Hug?

Block, A. E., Kuchenbecker, K. J.

Work-in-progress paper (2 pages) presented at the IEEE World Haptics Conference (WHC), Munich, Germany, June 2017 (misc)

hi

Project Page [BibTex]

Project Page [BibTex]


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An Interactive Augmented-Reality Video Training Platform for the da Vinci Surgical System

Carlson, J., Kuchenbecker, K. J.

Workshop paper (3 pages) presented at the ICRA Workshop on C4 Surgical Robots, Singapore, May 2017 (misc)

Abstract
Teleoperated surgical robots such as the Intuitive da Vinci Surgical System facilitate minimally invasive surgeries, which decrease risk to patients. However, these systems can be difficult to learn, and existing training curricula on surgical simulators do not offer students the realistic experience of a full operation. This paper presents an augmented-reality video training platform for the da Vinci that will allow trainees to rehearse any surgery recorded by an expert. While the trainee operates a da Vinci in free space, they see their own instruments overlaid on the expert video. Tools are identified in the source videos via color segmentation and kernelized correlation filter tracking, and their depth is calculated from the da Vinci’s stereoscopic video feed. The user tries to follow the expert’s movements, and if any of their tools venture too far away, the system provides instantaneous visual feedback and pauses to allow the user to correct their motion. The trainee can also rewind the expert video by bringing either da Vinci tool very close to the camera. This combined and augmented video provides the user with an immersive and interactive training experience.

hi

[BibTex]

[BibTex]


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Estimating B0 inhomogeneities with projection FID navigator readouts

Loktyushin, A., Ehses, P., Schölkopf, B., Scheffler, K.

25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), April 2017 (poster)

ei

link (url) [BibTex]

link (url) [BibTex]


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Image Quality Improvement by Applying Retrospective Motion Correction on Quantitative Susceptibility Mapping and R2*

Feng, X., Loktyushin, A., Deistung, A., Reichenbach, J.

25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM), April 2017 (poster)

ei

link (url) [BibTex]

link (url) [BibTex]


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Hand-Clapping Games with a Baxter Robot

Fitter, N. T., Kuchenbecker, K. J.

Hands-on demonstration presented at ACM/IEEE International Conference on Human-Robot Interaction (HRI), Vienna, Austria, March 2017 (misc)

Abstract
Robots that work alongside humans might be more effective if they could forge a strong social bond with their human partners. Hand-clapping games and other forms of rhythmic social-physical interaction may foster human-robot teamwork, but the design of such interactions has scarcely been explored. At the HRI 2017 conference, we will showcase several such interactions taken from our recent work with the Rethink Robotics Baxter Research Robot, including tempo-matching, Simon says, and Pat-a-cake-like games. We believe conference attendees will be both entertained and intrigued by this novel demonstration of social-physical HRI.

hi

Project Page [BibTex]

Project Page [BibTex]


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Automatic OSATS Rating of Trainee Skill at a Pediatric Laparoscopic Suturing Task

Oquendo, Y. A., Riddle, E. W., Hiller, D., Blinman, T. A., Kuchenbecker, K. J.

Surgical Endoscopy, 31(Supplement 1):S28, Extended abstract presented as a podium presentation at the Annual Meeting of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES), Springer, Houston, USA, March 2017 (misc)

Abstract
Introduction: Minimally invasive surgery has revolutionized surgical practice, but challenges remain. Trainees must acquire complex technical skills while minimizing patient risk, and surgeons must maintain their skills for rare procedures. These challenges are magnified in pediatric surgery due to the smaller spaces, finer tissue, and relative dearth of both inanimate and virtual simulators. To build technical expertise, trainees need opportunities for deliberate practice with specific performance feedback, which is typically provided via tedious human grading. This study aimed to validate a novel motion-tracking system and machine learning algorithm for automatically evaluating trainee performance on a pediatric laparoscopic suturing task using a 1–5 OSATS Overall Skill rating. Methods: Subjects (n=14) ranging from medical students to fellows per- formed one or two trials of an intracorporeal suturing task in a custom pediatric laparoscopy training box (Fig. 1) after watching a video of ideal performance by an expert. The position and orientation of the tools and endoscope were recorded over time using Ascension trakSTAR magnetic motion-tracking sensors, and both instrument grasp angles were recorded over time using flex sensors on the handles. The 27 trials were video-recorded and scored on the OSATS scale by a senior fellow; ratings ranged from 1 to 4. The raw motion data from each trial was processed to calculate over 200 preliminary motion parameters. Regularized least-squares regression (LASSO) was used to identify the most predictive parameters for inclusion in a regression tree. Model performance was evaluated by leave-one-subject-out cross validation, wherein the automatic scores given to each subject’s trials (by a model trained on all other data) are compared to the corresponding human rater scores. Results: The best-performing LASSO algorithm identified 14 predictive parameters for inclusion in the regression tree, including completion time, linear path length, angular path length, angular acceleration, grasp velocity, and grasp acceleration. The final model’s raw output showed a strong positive correlation of 0.87 with the reviewer-generated scores, and rounding the output to the nearest integer yielded a leave-one-subject-out cross-validation accuracy of 77.8%. Results are summarized in the confusion matrix (Table 1). Conclusions: Our novel motion-tracking system and regression model automatically gave previously unseen trials overall skill scores that closely match scores from an expert human rater. With additional data and further development, this system may enable creation of a motion-based training platform for pediatric laparoscopic surgery and could yield insights into the fundamental components of surgical skill.

hi

[BibTex]

[BibTex]


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How Much Haptic Surface Data is Enough?

Burka, A., Kuchenbecker, K. J.

Workshop paper (5 pages) presented at the AAAI Spring Symposium on Interactive Multi-Sensory Object Perception for Embodied Agents, Stanford, USA, March 2017 (misc)

Abstract
The Proton Pack is a portable visuo-haptic surface interaction recording device that will be used to collect a vast multimodal dataset, intended for robots to use as part of an approach to understanding the world around them. In order to collect a useful dataset, we want to pick a suitable interaction duration for each surface, noting the tradeoff between data collection resources and completeness of data. One interesting approach frames the data collection process as an online learning problem, building an incremental surface model and using that model to decide when there is enough data. Here we examine how to do such online surface modeling and when to stop collecting data, using kinetic friction as a first domain in which to apply online modeling.

hi

link (url) Project Page [BibTex]

link (url) Project Page [BibTex]


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Generalized phase locking analysis of electrophysiology data

Safavi, S., Panagiotaropoulos, T., Kapoor, V., Logothetis, N. K., Besserve, M.

ESI Systems Neuroscience Conference (ESI-SyNC 2017): Principles of Structural and Functional Connectivity, 2017 (poster)

ei

[BibTex]

[BibTex]

2006


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Some observations on the pedestal effect or dipper function

Henning, B., Wichmann, F.

Journal of Vision, 6(13):50, 2006 Fall Vision Meeting of the Optical Society of America, December 2006 (poster)

Abstract
The pedestal effect is the large improvement in the detectabilty of a sinusoidal “signal” grating observed when the signal is added to a masking or “pedestal” grating of the same spatial frequency, orientation, and phase. We measured the pedestal effect in both broadband and notched noise - noise from which a 1.5-octave band centred on the signal frequency had been removed. Although the pedestal effect persists in broadband noise, it almost disappears in the notched noise. Furthermore, the pedestal effect is substantial when either high- or low-pass masking noise is used. We conclude that the pedestal effect in the absence of notched noise results principally from the use of information derived from channels with peak sensitivities at spatial frequencies different from that of the signal and pedestal. The spatial-frequency components of the notched noise above and below the spatial frequency of the signal and pedestal prevent the use of information about changes in contrast carried in channels tuned to spatial frequencies that are very much different from that of the signal and pedestal. Thus the pedestal or dipper effect measured without notched noise is not a characteristic of individual spatial-frequency tuned channels.

ei

Web DOI [BibTex]

2006


Web DOI [BibTex]


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A Kernel Method for the Two-Sample-Problem

Gretton, A., Borgwardt, K., Rasch, M., Schölkopf, B., Smola, A.

20th Annual Conference on Neural Information Processing Systems (NIPS), December 2006 (talk)

Abstract
We propose two statistical tests to determine if two samples are from different distributions. Our test statistic is in both cases the distance between the means of the two samples mapped into a reproducing kernel Hilbert space (RKHS). The first test is based on a large deviation bound for the test statistic, while the second is based on the asymptotic distribution of this statistic. We show that the test statistic can be computed in $O(m^2)$ time. We apply our approach to a variety of problems, including attribute matching for databases using the Hungarian marriage method, where our test performs strongly. We also demonstrate excellent performance when comparing distributions over graphs, for which no alternative tests currently exist.

ei

PDF [BibTex]

PDF [BibTex]


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Ab-initio gene finding using machine learning

Schweikert, G., Zeller, G., Zien, A., Ong, C., de Bona, F., Sonnenburg, S., Phillips, P., Rätsch, G.

NIPS Workshop on New Problems and Methods in Computational Biology, December 2006 (talk)

ei

Web [BibTex]

Web [BibTex]


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Graph boosting for molecular QSAR analysis

Saigo, H., Kadowaki, T., Kudo, T., Tsuda, K.

NIPS Workshop on New Problems and Methods in Computational Biology, December 2006 (talk)

Abstract
We propose a new boosting method that systematically combines graph mining and mathematical programming-based machine learning. Informative and interpretable subgraph features are greedily found by a series of graph mining calls. Due to our mathematical programming formulation, subgraph features and pre-calculated real-valued features are seemlessly integrated. We tested our algorithm on a quantitative structure-activity relationship (QSAR) problem, which is basically a regression problem when given a set of chemical compounds. In benchmark experiments, the prediction accuracy of our method favorably compared with the best results reported on each dataset.

ei

Web [BibTex]

Web [BibTex]


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Inferring Causal Directions by Evaluating the Complexity of Conditional Distributions

Sun, X., Janzing, D., Schölkopf, B.

NIPS Workshop on Causality and Feature Selection, December 2006 (talk)

Abstract
We propose a new approach to infer the causal structure that has generated the observed statistical dependences among n random variables. The idea is that the factorization of the joint measure of cause and effect into P(cause)P(effect|cause) leads typically to simpler conditionals than non-causal factorizations. To evaluate the complexity of the conditionals we have tried two methods. First, we have compared them to those which maximize the conditional entropy subject to the observed first and second moments since we consider the latter as the simplest conditionals. Second, we have fitted the data with conditional probability measures being exponents of functions in an RKHS space and defined the complexity by a Hilbert-space semi-norm. Such a complexity measure has several properties that are useful for our purpose. We describe some encouraging results with both methods applied to real-world data. Moreover, we have combined constraint-based approaches to causal discovery (i.e., methods using only information on conditional statistical dependences) with our method in order to distinguish between causal hypotheses which are equivalent with respect to the imposed independences. Furthermore, we compare the performance to Bayesian approaches to causal inference.

ei

Web [BibTex]


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Learning Optimal EEG Features Across Time, Frequency and Space

Farquhar, J., Hill, J., Schölkopf, B.

NIPS Workshop on Current Trends in Brain-Computer Interfacing, December 2006 (talk)

ei

PDF Web [BibTex]

PDF Web [BibTex]


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Semi-Supervised Learning

Zien, A.

Advanced Methods in Sequence Analysis Lectures, November 2006 (talk)

ei

Web [BibTex]

Web [BibTex]


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Optimizing Spatial Filters for BCI: Margin- and Evidence-Maximization Approaches

Farquhar, J., Hill, N., Schölkopf, B.

Challenging Brain-Computer Interfaces: MAIA Workshop 2006, pages: 1, November 2006 (poster)

Abstract
We present easy-to-use alternatives to the often-used two-stage Common Spatial Pattern + classifier approach for spatial filtering and classification of Event-Related Desychnronization signals in BCI. We report two algorithms that aim to optimize the spatial filters according to a criterion more directly related to the ability of the algorithms to generalize to unseen data. Both are based upon the idea of treating the spatial filter coefficients as hyperparameters of a kernel or covariance function. We then optimize these hyper-parameters directly along side the normal classifier parameters with respect to our chosen learning objective function. The two objectives considered are margin maximization as used in Support-Vector Machines and the evidence maximization framework used in Gaussian Processes. Our experiments assessed generalization error as a function of the number of training points used, on 9 BCI competition data sets and 5 offline motor imagery data sets measured in Tubingen. Both our approaches sho w consistent improvements relative to the commonly used CSP+linear classifier combination. Strikingly, the improvement is most significant in the higher noise cases, when either few trails are used for training, or with the most poorly performing subjects. This a reversal of the usual "rich get richer" effect in the development of CSP extensions, which tend to perform best when the signal is strong enough to accurately find their additional parameters. This makes our approach particularly suitable for clinical application where high levels of noise are to be expected.

ei

PDF PDF [BibTex]

PDF PDF [BibTex]


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A Machine Learning Approach for Determining the PET Attenuation Map from Magnetic Resonance Images

Hofmann, M., Steinke, F., Judenhofer, M., Claussen, C., Schölkopf, B., Pichler, B.

IEEE Medical Imaging Conference, November 2006 (talk)

Abstract
A promising new combination in multimodality imaging is MR-PET, where the high soft tissue contrast of Magnetic Resonance Imaging (MRI) and the functional information of Positron Emission Tomography (PET) are combined. Although many technical problems have recently been solved, it is still an open problem to determine the attenuation map from the available MR scan, as the MR intensities are not directly related to the attenuation values. One standard approach is an atlas registration where the atlas MR image is aligned with the patient MR thus also yielding an attenuation image for the patient. We also propose another approach, which to our knowledge has not been tried before: Using Support Vector Machines we predict the attenuation value directly from the local image information. We train this well-established machine learning algorithm using small image patches. Although both approaches sometimes yielded acceptable results, they also showed their specific shortcomings: The registration often fails with large deformations whereas the prediction approach is problematic when the local image structure is not characteristic enough. However, the failures often do not coincide and integration of both information sources is promising. We therefore developed a combination method extending Support Vector Machines to use not only local image structure but also atlas registered coordinates. We demonstrate the strength of this combination approach on a number of examples.

ei

[BibTex]

[BibTex]


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Semi-Supervised Support Vector Machines and Application to Spam Filtering

Zien, A.

ECML Discovery Challenge Workshop, September 2006 (talk)

Abstract
After introducing the semi-supervised support vector machine (aka TSVM for "transductive SVM"), a few popular training strategies are briefly presented. Then the assumptions underlying semi-supervised learning are reviewed. Finally, two modern TSVM optimization techniques are applied to the spam filtering data sets of the workshop; it is shown that they can achieve excellent results, if the problem of the data being non-iid can be handled properly.

ei

PDF Web [BibTex]


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Learning Eye Movements

Kienzle, W., Wichmann, F., Schölkopf, B., Franz, M.

Sensory Coding And The Natural Environment, 2006, pages: 1, September 2006 (poster)

Abstract
The human visual system samples images through saccadic eye movements which rapidly change the point of fixation. Although the selection of eye movement targets depends on numerous top-down mechanisms, a number of recent studies have shown that low-level image features such as local contrast or edges play an important role. These studies typically used predefined image features which were afterwards experimentally verified. Here, we follow a complementary approach: instead of testing a set of candidate image features, we infer these hypotheses from the data, using methods from statistical learning. To this end, we train a non-linear classifier on fixated vs. randomly selected image patches without making any physiological assumptions. The resulting classifier can be essentially characterized by a nonlinear combination of two center-surround receptive fields. We find that the prediction performance of this simple model on our eye movement data is indistinguishable from the physiologically motivated model of Itti & Koch (2000) which is far more complex. In particular, we obtain a comparable performance without using any multi-scale representations, long-range interactions or oriented image features.

ei

Web [BibTex]

Web [BibTex]


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Inferential Structure Determination: Probabilistic determination and validation of NMR structures

Habeck, M.

Gordon Research Conference on Computational Aspects of Biomolecular NMR, September 2006 (talk)

ei

Web [BibTex]

Web [BibTex]


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Machine Learning Algorithms for Polymorphism Detection

Schweikert, G., Zeller, G., Clark, R., Ossowski, S., Warthmann, N., Shinn, P., Frazer, K., Ecker, J., Huson, D., Weigel, D., Schölkopf, B., Rätsch, G.

2nd ISCB Student Council Symposium, August 2006 (talk)

Abstract
Analyzing resequencing array data using machine learning, we obtain a genome-wide inventory of polymorphisms in 20 wild strains of Arabidopsis thaliana, including 750,000 single nucleotide poly- morphisms (SNPs) and thousands of highly polymorphic regions and deletions. We thus provide an unprecedented resource for the study of natural variation in plants.

ei

Web [BibTex]

Web [BibTex]


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Inferential structure determination: Overview and new developments

Habeck, M.

Sixth CCPN Annual Conference: Efficient and Rapid Structure Determination by NMR, July 2006 (talk)

ei

Web [BibTex]

Web [BibTex]


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Classification of natural scenes: Critical features revisited

Drewes, J., Wichmann, F., Gegenfurtner, K.

Journal of Vision, 6(6):561, 6th Annual Meeting of the Vision Sciences Society (VSS), June 2006 (poster)

Abstract
Human observers are capable of detecting animals within novel natural scenes with remarkable speed and accuracy. Despite the seeming complexity of such decisions it has been hypothesized that a simple global image feature, the relative abundance of high spatial frequencies at certain orientations, could underly such fast image classification (A. Torralba & A. Oliva, Network: Comput. Neural Syst., 2003). We successfully used linear discriminant analysis to classify a set of 11.000 images into “animal” and “non-animal” images based on their individual amplitude spectra only (Drewes, Wichmann, Gegenfurtner VSS 2005). We proceeded to sort the images based on the performance of our classifier, retaining only the best and worst classified 400 images (“best animals”, “best distractors” and “worst animals”, “worst distractors”). We used a Go/No-go paradigm to evaluate human performance on this subset of our images. Both reaction time and proportion of correctly classified images showed a significant effect of classification difficulty. Images more easily classified by our algorithm were also classified faster and better by humans, as predicted by the Torralba & Oliva hypothesis. We then equated the amplitude spectra of the 400 images, which, by design, reduced algorithmic performance to chance whereas human performance was only slightly reduced (cf. Wichmann, Rosas, Gegenfurtner, VSS 2005). Most importantly, the same images as before were still classified better and faster, suggesting that even in the original condition features other than specifics of the amplitude spectrum made particular images easy to classify, clearly at odds with the Torralba & Oliva hypothesis.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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MCMC inference in (Conditionally) Conjugate Dirichlet Process Gaussian Mixture Models

Rasmussen, C., Görür, D.

ICML Workshop on Learning with Nonparametric Bayesian Methods, June 2006 (talk)

Abstract
We compare the predictive accuracy of the Dirichlet Process Gaussian mixture models using conjugate and conditionally conjugate priors and show that better density models result from using the wider class of priors. We explore several MCMC schemes exploiting conditional conjugacy and show their computational merits on several multidimensional density estimation problems.

ei

Web [BibTex]

Web [BibTex]


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Sampling for non-conjugate infinite latent feature models

Görür, D., Rasmussen, C.

(Editors: Bernardo, J. M.), 8th Valencia International Meeting on Bayesian Statistics (ISBA), June 2006 (talk)

Abstract
Latent variable models are powerful tools to model the underlying structure in data. Infinite latent variable models can be defined using Bayesian nonparametrics. Dirichlet process (DP) models constitute an example of infinite latent class models in which each object is assumed to belong to one of the, mutually exclusive, infinitely many classes. Recently, the Indian buffet process (IBP) has been defined as an extension of the DP. IBP is a distribution over sparse binary matrices with infinitely many columns which can be used as a distribution for non-exclusive features. Inference using Markov chain Monte Carlo (MCMC) in conjugate IBP models has been previously described, however requiring conjugacy restricts the use of IBP. We describe an MCMC algorithm for non-conjugate IBP models. Modelling the choice behaviour is an important topic in psychology, economics and related fields. Elimination by Aspects (EBA) is a choice model that assumes each alternative has latent features with associated weights that lead to the observed choice outcomes. We formulate a non-parametric version of EBA by using IBP as the prior over the latent binary features. We infer the features of objects that lead to the choice data by using our sampling scheme for inference.

ei

PDF [BibTex]

PDF [BibTex]


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The pedestal effect is caused by off-frequency looking, not nonlinear transduction or contrast gain-control

Wichmann, F., Henning, B.

Journal of Vision, 6(6):194, 6th Annual Meeting of the Vision Sciences Society (VSS), June 2006 (poster)

Abstract
The pedestal or dipper effect is the large improvement in the detectabilty of a sinusoidal grating observed when the signal is added to a pedestal or masking grating having the signal‘s spatial frequency, orientation, and phase. The effect is largest with pedestal contrasts just above the ‘threshold‘ in the absence of a pedestal. We measured the pedestal effect in both broadband and notched masking noise---noise from which a 1.5- octave band centered on the signal and pedestal frequency had been removed. The pedestal effect persists in broadband noise, but almost disappears with notched noise. The spatial-frequency components of the notched noise that lie above and below the spatial frequency of the signal and pedestal prevent the use of information about changes in contrast carried in channels tuned to spatial frequencies that are very much different from that of the signal and pedestal. We conclude that the pedestal effect in the absence of notched noise results principally from the use of information derived from channels with peak sensitivities at spatial frequencies that are different from that of the signal and pedestal. Thus the pedestal or dipper effect is not a characteristic of individual spatial-frequency tuned channels.

ei

Web DOI [BibTex]

Web DOI [BibTex]


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An Inventory of Sequence Polymorphisms For Arabidopsis

Clark, R., Ossowski, S., Schweikert, G., Rätsch, G., Shinn, P., Zeller, G., Warthmann, N., Fu, G., Hinds, D., Chen, H., Frazer, K., Huson, D., Schölkopf, B., Nordborg, M., Ecker, J., Weigel, D.

17th International Conference on Arabidopsis Research, April 2006 (talk)

Abstract
We have used high-density oligonucleotide arrays to characterize common sequence variation in 20 wild strains of Arabidopsis thaliana that were chosen for maximal genetic diversity. Both strands of each possible SNP of the 119 Mb reference genome were represented on the arrays, which were hybridized with whole genome, isothermally amplified DNA to minimize ascertainment biases. Using two complementary approaches, a model based algorithm, and a newly developed machine learning method, we identified over 550,000 SNPs with a false discovery rate of ~ 0.03 (average of 1 SNP for every 216 bp of the genome). A heuristic algorithm predicted in addition ~700 highly polymorphic or deleted regions per accession. Over 700 predicted polymorphisms with major functional effects (e.g., premature stop codons, or deletions of coding sequence) were validated by dideoxy sequencing. Using this data set, we provide the first systematic description of the types of genes that harbor major effect polymorphisms in natural populations at moderate allele frequencies. The data also provide an unprecedented resource for the study of genetic variation in an experimentally tractable, multicellular model organism.

ei

[BibTex]

[BibTex]


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The Pedestal Effect is Caused by Off-Frequency Looking, not Nonlinear Transduction or Contrast Gain-Control

Wichmann, F., Henning, G.

9, pages: 174, 9th T{\"u}bingen Perception Conference (TWK), March 2006 (poster)

Abstract
The pedestal or dipper effect is the large improvement in the detectability of a sinusoidal grating observed when the signal is added to a pedestal or masking grating having the signal‘s spatial frequency, orientation, and phase. The effect is largest with pedestal contrasts just above the ‘threshold’ in the absence of a pedestal. We measured the pedestal effect in both broadband and notched masking noise---noise from which a 1.5-octave band centered on the signal and pedestal frequency had been removed. The pedestal effect persists in broadband noise, but almost disappears with notched noise. The spatial-frequency components of the notched noise that lie above and below the spatial frequency of the signal and pedestal prevent the use of information about changes in contrast carried in channels tuned to spatial frequencies that are very much different from that of the signal and pedestal. We conclude that the pedestal effect in the absence of notched noise results principally from the use of information derived from channels with peak sensitivities at spatial frequencies that are different from that of the signal and pedestal. Thus the pedestal or dipper effect is not a characteristic of individual spatial-frequency tuned channels.

ei

Web [BibTex]

Web [BibTex]


no image
Classification of Natural Scenes: Critical Features Revisited

Drewes, J., Wichmann, F., Gegenfurtner, K.

9, pages: 92, 9th T{\"u}bingen Perception Conference (TWK), March 2006 (poster)

Abstract
Human observers are capable of detecting animals within novel natural scenes with remarkable speed and accuracy. Despite the seeming complexity of such decisions it has been hypothesized that a simple global image feature, the relative abundance of high spatial frequencies at certain orientations, could underly such fast image classification [1]. We successfully used linear discriminant analysis to classify a set of 11.000 images into “animal” and “non-animal” images based on their individual amplitude spectra only [2]. We proceeded to sort the images based on the performance of our classifier, retaining only the best and worst classified 400 images ("best animals", "best distractors" and "worst animals", "worst distractors"). We used a Go/No-go paradigm to evaluate human performance on this subset of our images. Both reaction time and proportion of correctly classified images showed a significant effect of classification difficulty. Images more easily classified by our algorithm were also classified faster and better by humans, as predicted by the Torralba & Oliva hypothesis. We then equated the amplitude spectra of the 400 images, which, by design, reduced algorithmic performance to chance whereas human performance was only slightly reduced [3]. Most importantly, the same images as before were still classified better and faster, suggesting that even in the original condition features other than specifics of the amplitude spectrum made particular images easy to classify, clearly at odds with the Torralba & Oliva hypothesis.

ei

Web [BibTex]

Web [BibTex]


no image
Factorial Coding of Natural Images: How Effective are Linear Models in Removing Higher-Order Dependencies?

Bethge, M.

9, pages: 90, 9th T{\"u}bingen Perception Conference (TWK), March 2006 (poster)

Abstract
The performance of unsupervised learning models for natural images is evaluated quantitatively by means of information theory. We estimate the gain in statistical independence (the multi-information reduction) achieved with independent component analysis (ICA), principal component analysis (PCA), zero-phase whitening, and predictive coding. Predictive coding is translated into the transform coding framework, where it can be characterized by the constraint of a triangular filter matrix. A randomly sampled whitening basis and the Haar wavelet are included into the comparison as well. The comparison of all these methods is carried out for different patch sizes, ranging from 2x2 to 16x16 pixels. In spite of large differences in the shape of the basis functions, we find only small differences in the multi-information between all decorrelation transforms (5% or less) for all patch sizes. Among the second-order methods, PCA is optimal for small patch sizes and predictive coding performs best for large patch sizes. The extra gain achieved with ICA is always less than 2%. In conclusion, the `edge filters‘ found with ICA lead only to a surprisingly small improvement in terms of its actual objective.

ei

Web [BibTex]

Web [BibTex]


no image
Classification of natural scenes: critical features revisited

Drewes, J., Wichmann, F., Gegenfurtner, K.

Experimentelle Psychologie: Beitr{\"a}ge zur 48. Tagung experimentell arbeitender Psychologen, 48, pages: 251, 2006 (poster)

ei

[BibTex]

[BibTex]


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Texture and haptic cues in slant discrimination: combination is sensitive to reliability but not statistically optimal

Rosas, P., Wagemans, J., Ernst, M., Wichmann, F.

Beitr{\"a}ge zur 48. Tagung experimentell arbeitender Psychologen (TeaP 2006), 48, pages: 80, 2006 (poster)

ei

[BibTex]

[BibTex]


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Ähnlichkeitsmasse in Modellen zur Kategorienbildung

Jäkel, F., Wichmann, F.

Experimentelle Psychologie: Beitr{\"a}ge zur 48. Tagung experimentell arbeitender Psychologen, 48, pages: 223, 2006 (poster)

ei

[BibTex]

[BibTex]


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The pedestal effect is caused by off-frequency looking, not nonlinear transduction or contrast gain-control

Wichmann, F., Henning, B.

Experimentelle Psychologie: Beitr{\"a}ge zur 48. Tagung experimentell arbeitender Psychologen, 48, pages: 205, 2006 (poster)

ei

[BibTex]

[BibTex]